DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment VhaPPA1-2 and atp6v0b

DIOPT Version :9

Sequence 1:	NP_650406.2	Gene:	VhaPPA1-2 / 41806	FlyBaseID:	FBgn0262514	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_001017064.1	Gene:	atp6v0b / 549818	XenbaseID:	XB-GENE-997920	Length:	205	Species:	Xenopus tropicalis

Alignment Length:	191	Identity:	108/191 - (56%)
Similarity:	140/191 - (73%)	Gaps:	5/191 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 ASLGAVGIIFANVMVNMGERMGLGWFLYTSNPFLWSGMGIFLACALSVLGAASGIYMIGCSVAGG 83
            |:|..||..:  .:.::|.|..:.|||..::|::|:.:||.|:.:|||:|||.|||:.|.|:.||
Frog    17 ATLIIVGTCY--TIFDLGFRFDVAWFLTETSPYMWANLGIGLSISLSVVGAAWGIYITGSSILGG 79

  Fly    84 GVRSPRIKTKNLISVIFCEAVAIYGLITAILLSGNVNKFSSVRLITDSTVMATNMFTGFATFGAG 148
            ||::||||||||:|:||||||||||:|.||::|....:|...   |...:.:.|...||:.||||
Frog    80 GVKAPRIKTKNLVSIIFCEAVAIYGIIMAIVISNMAEQFKGT---TPEAIGSRNYHAGFSMFGAG 141

  Fly   149 LCVGMVNVACGIAVGIVGSGAALADAANSALFVKILIVEIFGSAIGLFGLIVAIYMTSKAE 209
            |.||..|:.|||.|||||||||||||.|.:|||||||||||||||||||:||||..|||.:
Frog   142 LTVGFSNLFCGICVGIVGSGAALADAQNPSLFVKILIVEIFGSAIGLFGVIVAILQTSKVK 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
VhaPPA1-2	NP_650406.2	ATP-synt_C	56..166	CDD:294318	60/109 (55%)
VhaPPA1-2	NP_650406.2	ATP-synt_C	143..204	CDD:278563	48/60 (80%)
atp6v0b	NP_001017064.1	ATP-synt_C	52..111	CDD:306615	40/58 (69%)
atp6v0b	NP_001017064.1	ATP-synt_C	138..196	CDD:306615	47/57 (82%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	95	1.000	Domainoid score	I7291
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	227	1.000	Inparanoid score	I3397
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1408246at2759
OrthoFinder	1	1.000	-	-		FOG0002690
OrthoInspector	1	1.000	-	-		otm48294
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2155
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.060