DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Nup93-2 and AT3G57350

DIOPT Version :9

Sequence 1:	NP_650404.1	Gene:	Nup93-2 / 41804	FlyBaseID:	FBgn0038274	Length:	796	Species:	Drosophila melanogaster
Sequence 2:	NP_191294.5	Gene:	AT3G57350 / 824902	AraportID:	AT3G57350	Length:	860	Species:	Arabidopsis thaliana

Alignment Length:	853	Identity:	181/853 - (21%)
Similarity:	331/853 - (38%)	Gaps:	171/853 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LLQRAQNLNNDAKAECELPAVERTLQQVLRATTELHSRV--TQTGCKEIQAHILLGSKGVDLPKL 68
            ||..:..|...|....:.|.::|.|.|:...:.:|.::.  .:...:.|.|..||..:|::..:|
plant    13 LLHSSTKLLEQAAPSSQFPPLQRNLDQLEALSRKLKAKTLRNEAPSQSIAATRLLAREGINADQL 77

  Fly    69 NQKLEALSARKTFEPLDVKADTDVRTFLKNERENAILSVIEDTKKNISDSANKQRWASMNKVWNE 133
            ::.|::...:.|||.:.....|.|..:|:...|.|::|.|::.:|:...|.|..    |.||..|
plant    78 SRDLKSFELKTTFEDVFPAETTSVEEYLQQVHEMAMVSAIQEAQKDNVRSFNNY----MLKVLEE 138

  Fly   134 ----EKTRLLDALIAPSQNFIDLQRLPEPTIVN-----------PLCQPRSCLDPLELV------ 177
                ||...|.:|...|.       ||:..::|           ||....|.....|||
plant   139 DCIKEKRDFLHSLSKTSM-------LPKTKMINSSRGSHAGSLVPLSPQVSSKPGTELVSMTNKP 196

  Fly   178 -YAQELRHYNELL--LKSSHRPNLVQKFAHLSQSFGD-----------CRLTDMWTLLACVTQIS 228
             :.::...|.|::  |.|:....|..|.|.|.....:           ..:..:|.|:..:|...
plant   197 IHEKKAYVYAEVVKKLNSARERGLPFKLATLFNGAYESLEIDLTRGKSVNMQKLWQLIQGMTGEE 261

  Fly   229 EPLRSDPIKSRQQRPEFVTYAKSYLERRYRVFMCSQV---------GGSYANNSYQLVVAYVNHR 284
            ..::....|    |...|..|:.:||..:...:...:         |||..|  .|.:.|::..|
plant   262 SAVQHGVSK----RMALVIGARRHLECGHGKHIMDTIQSHPTQAALGGSVGN--LQRIRAFLRIR 320

  Fly   285 FRAQQTIGL--VDTVREIPL---WPLVYYGLRCGAVKVAVEFLREAGSSHDEFAQL--------- 335
            .|...::..  ||..|:.|:   |..:|:.||.|..:.|.|..:.:.||..:||.|
plant   321 LRDYGSLDFDSVDARRQPPVDTTWQQIYFCLRTGYYEEAREIAQSSRSSQQQFAPLLTEWITTGG 385

  Fly   336 -VADRNAGETNSKIENQLRLQYANKIRNST-DAYKKAVYCILLGC--DVNEVHGEVA---KTIDD 393
             ||.:.|...:.:.|..||:  .::...:| |..|..:|.|:.|.  .::.:..:.:   .||:|
plant   386 TVAAQTAATASEECEKLLRM--GDRFGQTTYDKKKLLLYTIISGSRRQIDRIMRDFSTLFNTIED 448

  Fly   394 FLWMRLAMIQPGDADNYGKLQSMI------------LEQYGEK-----YFNARQQPYLYFETLAL 441
            |||.:|:.::    |..|...|||            |:.|..|     |....:.|.:|...|.|
plant   449 FLWFKLSCVR----DVAGGSSSMIVNDGLVPYSLDDLQAYLNKFEPSYYTKNGKDPLVYPYVLLL 509

  Fly   442 TGQFEAAIEFLARQ--DEN-RAHAVHMAIALFELGLLGSARSVSQPLLSIDIKDPQPLRRLNLTR 503
            :.|...||..::.:  ||. ...|||:||:|.:..:|.......:.|..:|       .....:.
plant   510 SIQLLPAIMHMSNEAGDEGYNIDAVHVAISLVDHSILSEGSGTGRKLSVMD-------ANAEASS 567

  Fly   504 LIRQYVQRF-ERTDTSEALHYY-------------YTLRCLKD-SKGRNMFMACVCDLVV--DSG 551
            :||||...: ...|....|.||             ::.|...| .:.||:.:..:...::  :.|
plant   568 MIRQYGSMYLHHGDLQMTLEYYAQAAIAVGGGQQAWSGRSNVDQQRQRNLMLKQLLTEILSQEDG 632

  Fly   552 VFDTTIFDLIFGKRQSSDQNDVNSGLFRQFECPEFDTR-TMAAQVGDELAALGNFEMSARLYEMA 615
            :      ..:.|.|.|.::.::...|      |:...| ....:...:....|.::.|..|.:..
plant   633 I------HFLLGARGSGEEGELGRFL------PDIKLRQQFLIEAAHQFQEAGLYDKSIELQKRV 685

  Fly   616 GKYNLAVKHI--CILMAQVVHLPTLGGSLRERLGQDAQRFNQLLASDSI--------DVEPK--- 667
            |.::.|::.|  |:..|       :...:|.|...:::....:|:.:.|        ||..:
plant   686 GAFSSALETINKCLSEA-------ICSLVRGRPDGESRTEGLVLSGNDILNSYKYHPDVSAQERH 743

  Fly   668 -MKSSFVLLQDLLIFFNFYHDGKFNAALDLLRQTQLVPNT-LD--DVDVVLGNVKQLSGEVIKVL 728
             :.....:|::|....:.:...:.|..||.:|:...:|.. ||  ..|......::.|......:
plant   744 LVMEQETILRELEAILSIHKLARLNKHLDAIREVAKLPFLHLDPRQPDTTSDEFQKASSYFQTCV 808

  Fly   729 PDVIVAAM 736
            ||::..|:
plant   809 PDLLKVAL 816

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nup93-2	NP_650404.1	DUF2461	178..>238	CDD:295279	11/72 (15%)
Nup93-2	NP_650404.1	Nic96	213..781	CDD:282017	126/609 (21%)
AT3G57350	NP_191294.5	Nic96	246..849	CDD:282017	126/609 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	62	1.000	Domainoid score	I3753
eggNOG	1	0.900	-	-		E1_KOG2168
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H40971
Inparanoid	1	1.050	91	1.000	Inparanoid score	I2268
OMA	1	1.010	-	-		QHG59183
OrthoDB	1	1.010	-	-		D187731at2759
OrthoFinder	1	1.000	-	-		FOG0002723
OrthoInspector	1	1.000	-	-		mtm1019
orthoMCL	1	0.900	-	-		OOG6_103333
Panther	1	1.100	-	-	LDO	PTHR11225
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840