Protein Alignment Nup93-2 and nup97

DIOPT Version :9

• Sequence 1: NP_650404.1
• Gene: Nup93-2 / 41804
• FlyBaseID: FBgn0038274
• Length: 796
• Species: Drosophila melanogaster
• Sequence 2: NP_588469.1
• Gene: nup97 / 2538861
• PomBaseID: SPCC1620.11
• Length: 851
• Species: Schizosaccharomyces pombe
• Alignment Length: 903
• Identity: 212/903 - (23%)
• Similarity: 371/903 - (41%)
• Gaps: 187/903 - (20%)

  Fly     8 QRAQNLNNDAKAECELPAVERTLQQVLRATTELHSRVTQTGCKEIQAHILLGSKGVDLPKLNQKL 72
            |:::.|.|:....| ||.::..|.::.:......:.|..:.....:||.||...|::..:..:|:
pombe    20 QKSRKLANELLEPC-LPFIQFNLGEIEQRAKHYLNTVPTSKDGNTKAHYLLAGSGINAEQTWKKI 83

  Fly    73 EALSAR----KTFEPLDVKADTDVRTFLKNERENAILSVIEDTKKNIS---DSANKQRW------ 124
            |:||.:    .|.|    .:.|||..|||..||..:|:.:|...:|..   |...::.|
pombe    84 ESLSLQVRPPTTLE----LSFTDVDMFLKYHREKNVLNSLEALVQNTQIAFDQYLEEEWRSKAAK 144

  Fly   125 --ASMNKVWNEEKTRL--LDALIAPSQNFIDLQRLPEPTIVNPLCQPRSCLDPLELVYAQELRHY 185
              .|.:.:..|.|.|:  ....:..||.|....::              ||:       :|..|.
pombe   145 SRPSFDNILLENKKRVSFYPFSVQRSQKFASTLKM--------------CLE-------EEALHG 188

  Fly   186 NELLLKSSHRPNLVQKFAHLSQSFGDCRLTDMWTLLACVTQISEPL-----------------RS 233
            .:..|.||. ..:.::|||.::|.   .|.:.|.||:.|....:.:                 ..
pombe   189 FQSKLVSSF-CEVAREFAHDTKSL---LLYESWKLLSSVILDKDSVTVFGNKGIISKAFDIETED 249

  Fly   234 DPIKSR-QQRPEFVTYAKSYLERRY---------RVFMCSQVGGSYANNSYQLVVAYVNHRFRAQ 288
            ..:.|| .||  ....::.:||.::         :....:.|||          |..:.::.||.
pombe   250 GSVNSRFYQR--ISDCSRKFLEAQFFEVLNKEIAKTPQAALVGG----------VPSIRNKIRAY 302

  Fly   289 QTIGL----------VDTVREIPLWPLVYYGLRCGAVKVAVEFLREAGSSHDEFAQ---LVADRN 340
            ..|.|          ::.::::|:|..::|.||||.:|.||:|..|.....::.|:   ...:..
pombe   303 LNIRLLRNGVWINPDLEIIQDVPIWAFIFYLLRCGFLKEAVDFTEENRDLFEKVAEKFPFYINAY 367

  Fly   341 AGETNSKIENQLRLQYAN------KIRNSTDAYKKAVYCILLGCDVNEVH-GEVAKTIDDFLWMR 398
            |...|..:..|||.|..:      :::.|:|.||.|||.|:..||:::.. ..:....:|::|.:
pombe   368 AKAPNGILPRQLRSQLFSEFNQTIRLQESSDPYKYAVYKIIGRCDLSKTSCPSICSVTEDYIWFQ 432

  Fly   399 LAMI-----QPGDADNYGKLQSM--ILEQYGEKYF-NARQQPYLYFETLALTGQFEAAIEFLARQ 455
            |.:.     :...|..:..|:.:  ||..||..|| |....|.:||..|.|.|.:|.||.||  .
pombe   433 LILSREFTEKSVSAHEFFSLEDVQHILLSYGSDYFTNNGSNPVMYFFLLMLCGLYERAINFL--Y 495

  Fly   456 DENRAHAVHMAIALFELGLLGSARSVS---------QPLLSIDIKDPQPLRRLNLTRLIRQYVQR 511
            ......|||.||.....|||.:|.|.|         |.:| ::.|..:|  .|...||:..|.|.
pombe   496 PYFPTDAVHFAITCAYYGLLRTAPSSSVVSNEPGKIQSML-VETKSGKP--SLEFDRLLIDYTQT 557

  Fly   512 FERTDTSEALHYYYTLRCLKDSKGRNMFMACVCDLVVDSGVFDTTIFDLI-FGKRQSSDQNDVNS 575
            .:  :.|..:...|.:...|..|..:|....:|.||:.:..:...:.|:. .|:|..|...:..|
pombe   558 CQ--ELSPVMSACYLIPMCKIDKYISMCHKSLCSLVLSTRDYVNLLGDIRGDGERTPSFLENHRS 620

  Fly   576 --GLFRQFECPEFDTRTMAAQVGDELAALGNFEMSARLYEMAGKYNLAVKHICILMAQVVHLPTL 638
              ||....|.....|.|.|.|..|:    |....:..||.:|..|:.||..|
pombe   621 LIGLSSVKEYLSKITLTAAKQADDQ----GLLSDAILLYHLAEDYDAAVTVI------------- 668

  Fly   639 GGSLRERLGQDAQRF-NQLLASDSI--------DVEPKMKSSFVLLQ-------DLLIF----FN 683
                ..|||....|| :|.:..|.:        ||..:..|.:..:.       :||:.    ||
pombe   669 ----NRRLGSALLRFLDQFVFPDKLISLTKSMMDVYNRNPSLYAKVDYKNRETTNLLLLTVEAFN 729

  Fly   684 FYHDGKFNAALDLLRQTQLVPNTLDDVD------VVLGNVKQ---LSGEVIKVLPDVIVAAMEIA 739
            .|.:..:..||..|:|.:::|  ||.:|      ||....|:   |:..:::.:|.:::.||...
pombe   730 AYTNKDYEQALSSLQQLEILP--LDPLDSDCETFVVRKLAKEFRFLNENLLQNVPGIVLIAMNSL 792

  Fly   740 QKQYKQLKAGS--GSSLEQTQMQQLRQRAKALSNMAATMPYRLPNDTNKRLIELELDM 795
            ::.|.:.|:.|  ..::...:::..||:|:.:...:..:.||:|:...::|...|::|
pombe   793 KELYAKQKSSSFGNDAISVDKLRLYRQKARRIVMYSFLIEYRMPSQILEQLNRCEIEM 850

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nup93-2	NP_650404.1	DUF2461	178..>238	CDD:295279	14/76 (18%)
		Nic96	213..781	CDD:282017	158/665 (24%)
nup97	NP_588469.1	Nic96	213..836	CDD:282017	158/664 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	117	1.000	Domainoid score	I1499
eggNOG	1	0.900	-	-		E1_KOG2168
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H40971
Inparanoid	1	1.050	146	1.000	Inparanoid score	I1329
OMA	1	1.010	-	-		QHG59183
OrthoFinder	1	1.000	-	-		FOG0002723
OrthoInspector	1	1.000	-	-		mtm9264
orthoMCL	1	0.900	-	-		OOG6_103333
Panther	1	1.100	-	-	LDO	PTHR11225
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R780
SonicParanoid	1	1.000	-	-		X3522
TreeFam	1	0.960	-	-
	14	13.860