Protein Alignment Nup93-2 and npp-13

DIOPT Version :10

• Sequence 1: NP_650404.1
• Gene: Nup93-2 / 41804
• FlyBaseID: FBgn0038274
• Length: 796
• Species: Drosophila melanogaster
• Sequence 2: NP_740802.1
• Gene: npp-13 / 171774
• WormBaseID: WBGene00003799
• Length: 787
• Species: Caenorhabditis elegans
• Alignment Length: 828
• Identity: 191/828 - (23%)
• Similarity: 349/828 - (42%)
• Gaps: 144/828 - (17%)

  Fly    26 VERTLQQVLRA-----TTELHSRVTQTGCKEIQAHILLGSKGVDLPKLNQKLEALSARKTFE--- 82
            ||:.|..:|..     |.:.||         :|..::.|.:|::||....|........|.|
 Worm    44 VEQELCGILGGSEGDWTRQTHS---------VQKQMMFGERGIELPSRQPKSHTAEDTLTDEGVV 99

  Fly    83 --PLDVKADTDVRTFLKNERENAILSVIEDTKKNISDSANKQRWAS--MNKVWNEEKTRLLDALI 143
              |..|..|.|     :.|.:..|..|..:|.:...:.....|.|:  ||.....|:    |.|.
 Worm   100 DVPEAVMDDID-----EEELDEDISRVKVETDRAFFNHMLLSRPAAVPMNPAQAMER----DNLP 155

  Fly   144 APSQNFIDLQRLPEPTIVNPLCQPRSCLDPLELVYAQELRHYNELLLKSSHRPNLVQKFAH-LSQ 207
            .....|::                ::..|..||::..:|..:    ||:..:.:||..... :.:
 Worm   156 FGGGKFVN----------------KNISDRRELIFGDKLHKF----LKNQGKKSLVDLMKEAIDE 200

  Fly   208 SFGDCRLTDMWTLLACVTQISEPLRSDPIKSRQQRPE---------FVTYAKSYLERRYRVFMCS 263
            |..|..|.|:|..:..|.........|.:.:.....|         |..:.::.:||...|   :
 Worm   201 SGTDGALGDVWNDVTSVLNRKTSASRDDLTTTANLVEDACKYLQAVFTEHMQTVVERNLEV---A 262

  Fly   264 QVGGSYANNSYQLVVAYV----NHRFRAQQTIGLVDTVREIPLWPLVYYGLRCGAVKVAVEFLRE 324
            :.||......  ||.|::    ...|:.:.     |::..:|.|.:.|:.:|.|.:|.|.|.|..
 Worm   263 ERGGIPGTRG--LVNAFLKVGTEESFQPED-----DSIDGMPTWQVTYHCVRAGDMKSASETLNR 320

  Fly   325 AGSSHDEFAQLVADRN----AGETNSKIENQLRLQYANKIRNSTDAYKKAVYCILL-GCDVNEVH 384
            . .|..:.|.|||..|    .|:.:|:::.:|::::.:.:.::.|.||:|:|..|| |.|    .
 Worm   321 L-KSFPQCATLVAALNHVAKHGKLDSELKKKLKVEWRHNLAHTKDKYKRALYAALLGGLD----S 380

  Fly   385 GEVAKTIDDFLWMRL--AMIQPGDAD-NYGKLQSMILEQYGEKYF--NARQQPYLYFETLALTGQ 444
            ..:|.|:::::|.:|  ..:.|...| .:.::|..:...|||:||  |...:...:|..|.|:||
 Worm   381 AALADTLENWIWFKLYPLHVDPQLTDVLFKEVQKAVSVDYGEQYFMSNGPSEFQYFFTALWLSGQ 445

  Fly   445 FEAAIEFLARQDENRAHAVHMAIALFELGLLGSARSVSQPLLSIDIKDPQPLRRLNLTRLIRQYV 509
            ||.|| :|..:...|..:||:|:...:||.|..::..:..:|.:|..|.... .|||.|||..|.
 Worm   446 FERAI-YLLHECGQRVDSVHVAVLAHKLGYLRMSKKSTDEMLVVDQNDSTKC-HLNLARLIVAYT 508

  Fly   510 QRFERTDTSEALHYYYTLRCLKDSKGRNMFMACVCDLVVDSGVFDTTIFDLIFGKRQSSDQNDVN 574
            :.||..|...:|.|::.|:.:....|.::|     ::.|...|:.|...|.|.||.....:.:
 Worm   509 KSFELVDVPRSLDYWFLLKGITTPTGSDVF-----EMAVSRSVYLTGQTDEILGKLTPDGRRE-- 566

  Fly   575 SGLFRQFECPEFDTRTMAAQVGDELAALGNFEMSARLYEMAGK-YNLAVKHICILMAQVVHLPTL 638
            .||..::   ..|...:..:|..:....|.::.:..||.:|.| .|.|:    :|.:::..  ||
 Worm   567 KGLIDEY---LDDPSEVICRVASDTEITGEWDQAVGLYLLASKPTNAAI----LLSSEISE--TL 622

  Fly   639 GGSLRERLGQDAQRFNQLLASDSIDVEPKMK-----------SSFVLLQDLLIFFNFYHDGKFNA 692
            ....:|::            :|.:.|..:.|           ::..||.||.:.|:...:.:...
 Worm   623 RTENKEKI------------ADLVHVAEQFKKVQRGCQASEYATLSLLVDLAVLFDHCRNEEAEI 675

  Fly   693 ALDLLRQTQLVPNTLDDVDVVLGNVKQLSGEVIKVLPDVIVAAME------IAQKQYKQLKAGSG 751
            |..:....:|:|...|.|.|::.....:..:|.:||||:.:..|:      |.|   ...:|..|
 Worm   676 AYGISTHLRLIPTEPDQVTVIVNEFHMVPQKVREVLPDMCLHLMKCLVDHCIRQ---STTQANRG 737

  Fly   752 SSLEQTQM----QQLRQRAKALSNMAATMPYRLPNDTNKRLIELELDM 795
            ::...|.|    .:..::.||:...:||:||:.|.....||::|:..:
 Worm   738 ANSATTSMFSSSNRYVKQIKAIVLYSATVPYKFPTHVTSRLLQLQASL 785

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nup93-2	NP_650404.1	Nic96	213..787	CDD:461172	147/618 (24%)
npp-13	NP_740802.1	Nic96	209..777	CDD:461172	146/615 (24%)