DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14860 and Thap1

DIOPT Version :9

Sequence 1:	NP_650403.2	Gene:	CG14860 / 41803	FlyBaseID:	FBgn0038273	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_950243.1	Gene:	Thap1 / 73754	MGIID:	1921004	Length:	210	Species:	Mus musculus

Alignment Length:	198	Identity:	41/198 - (20%)
Similarity:	71/198 - (35%)	Gaps:	50/198 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 IRRCSVRNCSSR---SPPERLHFFP-SNPEMRKAWMEICRLT--VDNKWLFICGRHFRRTYLPNK 155
            ::.||...|.:|   ..|...|.|| :.|.:.|.|....:..  ...|:..||..||.......:
Mouse     2 VQSCSAYGCKNRYDKDKPVSFHKFPLTRPSLCKQWEAAVKRKNFKPTKYSSICSEHFTPDCFKRE 66

  Fly   156 GN---LRKDAIPEFHLGTE----EED-----------PLGKSIKS-----MKSCANRSNISFKSE 197
            .|   |:::|:|...|..|    :||           |....:.:     |.......|:|...:
Mouse    67 CNNKLLKENAVPTIFLYIEPHEKKEDLESQEQLPSPSPPASQVDAAIGLLMPPLQTPDNLSVFCD 131

  Fly   198 DSGIDEESFKESKPHNNPCANCLDLQQQLAAAHLRIQQLEE--RRQE------------ETDSDD 248
            .:...|::..:.|       ..|.|:||:.....:::..::  ||||            :.:.||
Mouse   132 HNYTVEDTMHQRK-------RILQLEQQVEKLRKKLKTAQQRCRRQERQLEKLKEVVHFQREKDD 189

  Fly   249 DEE 251
            ..|
Mouse   190 ASE 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14860	NP_650403.2	DM3	24..80	CDD:128933
CG14860	NP_650403.2	DM3	114..169	CDD:128933	15/60 (25%)
Thap1	NP_950243.1	THAP	4..82	CDD:214951	20/77 (26%)
Thap1	NP_950243.1	HCFC1-binding motif (HBM). /evidence=ECO:0000250	131..134		0/2 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.870