DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14860 and l3mbtl2

DIOPT Version :9

Sequence 1:	NP_650403.2	Gene:	CG14860 / 41803	FlyBaseID:	FBgn0038273	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_956326.1	Gene:	l3mbtl2 / 568473	ZFINID:	ZDB-GENE-030131-8713	Length:	805	Species:	Danio rerio

Alignment Length:	162	Identity:	39/162 - (24%)
Similarity:	61/162 - (37%)	Gaps:	56/162 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RCIVTDCYK-SGQQDSSSMYKFPINPVVRQKWLDNIADIKDINLFN--SRVCRRHFETQC----- 63
            :|:...|.| |||  :.||::||.:|....||...:...:...|.|  |.:|..||...|
Zfish     4 KCVAYGCGKISGQ--NVSMFRFPKDPEEFSKWQRQVQKTRRNWLANTYSHLCNEHFTKDCFEPKT 66

  Fly    64 --------FGKTKVFSWAVPTLFLNTKEVVHQVSKPSRNSFIRRCSVRNCSSR------------ 108
                    |.:.|:...||||:|:.                 |||  |.|..:
Zfish    67 YVTAKASGFKRLKLKDGAVPTVFIR-----------------RRC--RKCGGKGVSCSFCIKKKQ 112

  Fly   109 ---SPPERLHFFPSNPEMRKAWMEICRLTVDN 137
               :.|::  |.|...||  .:|::.:...:|
Zfish   113 EALTQPQQ--FAPDEQEM--TFMDVTQNDGEN 140

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14860	NP_650403.2	DM3	24..80	CDD:128933	20/70 (29%)
CG14860	NP_650403.2	DM3	114..169	CDD:128933	6/24 (25%)
l3mbtl2	NP_956326.1	THAP	4..89	CDD:283206	26/86 (30%)
		MBT	257..357	CDD:214723
		MBT	366..467	CDD:214723
		MBT	511..582	CDD:280910
		MBT	591..682	CDD:214723
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910