DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14860 and thap1

DIOPT Version :9

Sequence 1:	NP_650403.2	Gene:	CG14860 / 41803	FlyBaseID:	FBgn0038273	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_001006738.1	Gene:	thap1 / 448407	XenbaseID:	XB-GENE-1008758	Length:	225	Species:	Xenopus tropicalis

Alignment Length:	220	Identity:	53/220 - (24%)
Similarity:	84/220 - (38%)	Gaps:	50/220 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 CIVTDCYKSGQQDSS-SMYKFPI-NPVVRQKWLDNI--ADIKDINLFNSRVCRRHFETQCFGK-- 66
            |....|.....:|.. |.:|||: .|::.:||...:  ||.|....  |.:|..||...||.:
Frog     5 CSAYGCKNRYDKDKPISFHKFPLKRPLLCRKWEAAVRRADFKPTKY--SSICSDHFTADCFKREC 67

  Fly    67 -TKVF-SWAVPTLFLNTKEVVHQVSKPSRNSFIRRCSVRNCSSRSPPERLHFFPSNPEMRKA-WM 128
             .|:. ..||||:|.:|     ::.|.|..      :|:.....:.||.:   ||.||:..| .:
Frog    68 NNKLLKDNAVPTIFAHT-----EIKKKSGK------AVKKEQLPAEPEPV---PSVPEVDPAIGL 118

  Fly   129 EICRLTVDNKWLFICGR--------HFRRTYLPNKGNLRKDAIPEFHLGTEEEDPLGKSIKSMKS 185
            .:..|...:....||..        |.||            .|.:..   |:.|.|.|.:|....
Frog   119 LLPPLYTPSHIAVICDHNYTVEDTVHQRR------------RIQQLE---EQVDKLRKKLKIANQ 168

  Fly   186 CANRSNISFKSEDSGIDEESFKESK 210
            ...|...|.:..:..:.|  ::|:|
Frog   169 KCRRQERSLEKLEREVSE--YREAK 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14860	NP_650403.2	DM3	24..80	CDD:128933	21/62 (34%)
CG14860	NP_650403.2	DM3	114..169	CDD:128933	12/63 (19%)
thap1	NP_001006738.1	THAP	5..81	CDD:368467	24/77 (31%)
thap1	NP_001006738.1	Tropomyosin_1	<147..184	CDD:372267	9/51 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910