DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14860 and si:dkey-250d21.1

DIOPT Version :9

Sequence 1:	NP_650403.2	Gene:	CG14860 / 41803	FlyBaseID:	FBgn0038273	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	XP_002663621.3	Gene:	si:dkey-250d21.1 / 402835	ZFINID:	ZDB-GENE-030131-8276	Length:	3614	Species:	Danio rerio

Alignment Length:	274	Identity:	66/274 - (24%)
Similarity:	101/274 - (36%)	Gaps:	95/274 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 CIVTDCYKSGQQDSSSMYKFPINPVVRQKWLD--NIADI-----KDINLFNSRVCRRHFET---- 61
            |...:|.:|..|.|.|.::||::|...::|:.  |..|:     :|::. |.:||.|||||
Zfish     5 CAAANCKQSTDQSSVSFFEFPLDPDRCRQWVGRCNRPDLQTKTPEDLHK-NYKVCSRHFETSMIC 68

  Fly    62 -----QCFGKTKVFSWAVPTLF-LNTKEVVHQVSKPSRNSFIRRCSVRNCSSRSP--PERLHFFP 118
                 :|..|..    |||||| .:|.:...|.||..|        .|..:...|  |::.....
Zfish    69 QQSAVKCILKDD----AVPTLFNFSTNQDNAQTSKRKR--------TREKTGEEPVVPKKTKGTT 121

  Fly   119 SNPEMRKAWMEICRLTVDNKWLFICGRHFRRTYLPNKGNLRKDAIPEFHLGTEEEDPLGKSIKSM 183
            .:|.:....||:          .:.|.....:.:.|         |..|..||:|||   :|...
Zfish   122 DDPNLSATEMEV----------KVEGVSAEISEIQN---------PPAHDETEKEDP---AISKA 164

  Fly   184 KSCANRSNISFKSEDSGIDEESFKE----------SKPHNNP---------CANCLDLQQQLAAA 229
            |.               |.:|.|||          :|...||         |:..:|.::.|...
Zfish   165 KE---------------ILKEYFKETLAFTGFSINNKASLNPGGTLSVNTMCSEKIDQKEVLTLG 214

  Fly   230 HLRIQQLEERRQEE 243
                   ||..:||
Zfish   215 -------EEVMREE 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14860	NP_650403.2	DM3	24..80	CDD:128933	23/72 (32%)
CG14860	NP_650403.2	DM3	114..169	CDD:128933	7/54 (13%)
si:dkey-250d21.1	XP_002663621.3	THAP	4..88	CDD:283206	29/87 (33%)
		DUF4371	<814..908	CDD:290989
		Ehrlichia_rpt	2107..2702	CDD:118064
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910