DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14860 and CG10631

DIOPT Version :9

Sequence 1:	NP_650403.2	Gene:	CG14860 / 41803	FlyBaseID:	FBgn0038273	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_609998.1	Gene:	CG10631 / 35262	FlyBaseID:	FBgn0032817	Length:	3781	Species:	Drosophila melanogaster

Alignment Length:	280	Identity:	68/280 - (24%)
Similarity:	122/280 - (43%)	Gaps:	35/280 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 NLRCIVTDCYKSGQQDSSSMYKFPINPVVRQKWLDNIADIKDINLFNSRVCRRHFETQCFGKTKV 69
            :|:|.|..|.:|..:..:.::.||.......||..|:....|....::|:|..||..:|....::
  Fly  1664 DLKCCVRSCGRSRLEHGARLFPFPTGKQQHLKWRHNLRLEPDEVDRSTRICSAHFNRRCIDGKQL 1728

  Fly    70 FSWAVPTLFLNTKE-VVHQVSKPSRNSFIRRCSVRNCSSRSPPE---RLHFFPSNPEMRKAWMEI 130
            .|||:||..|..:| .:::..|.....|...|::.:|..|...:   |.:.:|.:.::.:.|...
  Fly  1729 RSWAMPTQQLGHQEQPIYENPKNIPGFFTPTCALSHCRKRRSIDNDLRTYRYPRSEDLLEKWRAN 1793

  Fly   131 CRLTVDNKWLFICGRHFRRTYLPNKGNLRKDAIPEFHLG----------------TEEEDPLGKS 179
            .||..|.....||..|| .:.:..|..|:..|:|..:||                ||||:  |.|
  Fly  1794 LRLAPDQCRGRICADHF-ESQVRGKLKLKTGAVPTLNLGHDEGLIYDNEAIKVGMTEEEE--GSS 1855

  Fly   180 ----IKSMKSCANRSNISFKSEDSGIDEESFKESKP---HNNPCANCLDLQQQLAAAHLRIQQLE 237
                :|..:...:......::|:...:.:.:.|.:.   :.:|    |:|.:.. |.|....:.|
  Fly  1856 EMTRLKPKRELIDEEEEELEAEEEPHEHDMYDEDEKDGHYFDP----LELVETF-AEHPSDDEAE 1915

  Fly   238 ERRQEETDSDDDEEGEEEEH 257
            .|..||.:.|:||:.:|.||
  Fly  1916 YRGDEEDERDEDEDLDEAEH 1935

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14860	NP_650403.2	DM3	24..80	CDD:128933	16/55 (29%)
CG14860	NP_650403.2	DM3	114..169	CDD:128933	13/54 (24%)
CG10631	NP_609998.1	C2H2 Zn finger	288..311	CDD:275368
		C2H2 Zn finger	319..339	CDD:275368
		DM3	584..642	CDD:128933
		DM3	683..738	CDD:128933
		DM3	775..832	CDD:128933
		DM3	945..1000	CDD:128933
		DM3	1038..1096	CDD:128933
		DM3	1145..1198	CDD:128933
		THAP	1236..1308	CDD:214951
		DM3	1349..1406	CDD:128933
		THAP	1424..1493	CDD:214951
		DM3	1538..1596	CDD:128933
		DM3	1683..1739	CDD:128933	16/55 (29%)
		DM3	1778..1831	CDD:128933	13/53 (25%)
		DM3	1980..2033	CDD:128933
		DM3	2147..2202	CDD:128933
		DM3	2308..2365	CDD:128933
		DM3	2434..2491	CDD:128933
		DM3	2539..2598	CDD:128933
		DM3	2622..2680	CDD:128933
		DM3	2718..2775	CDD:128933
		DM3	2907..2965	CDD:128933
		DM3	3098..3155	CDD:128933
		DM3	3227..3284	CDD:128933
		DM3	3396..3452	CDD:128933
		DM3	3544..3601	CDD:128933
		THAP	3621..>3669	CDD:283206
		DM3	3690..3748	CDD:128933
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0020030
OrthoInspector	1	1.000	-	-		otm26404
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910