DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14860 and Thap12

DIOPT Version :9

Sequence 1:	NP_650403.2	Gene:	CG14860 / 41803	FlyBaseID:	FBgn0038273	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_001178559.1	Gene:	Thap12 / 308845	RGDID:	1309679	Length:	757	Species:	Rattus norvegicus

Alignment Length:	310	Identity:	73/310 - (23%)
Similarity:	120/310 - (38%)	Gaps:	91/310 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 CIVTDCYKSGQQDSSSMYKFPINPVVRQKWLDNI--ADIKD-----INLFNSRVCRRHFETQCFG 65
            |...:|.:...|...:.::||.:|...|||::|.  ||::|     :|. :.|:|.:||||....
  Rat     5 CAAPNCTRKSTQSDLAFFRFPRDPARCQKWVENCRRADLEDKTPDQLNK-HYRLCAKHFETSMIC 68

  Fly    66 KTKVFSW-----AVPTLF-----LNT---------KEVVHQVSKPSRNSFIRRCSVR----NCSS 107
            :|..:..     |:||:|     ||.         ||:.....:..:...|...|.:    |.::
  Rat    69 RTSPYRTVLRDNAIPTIFDLTSHLNNPHSRHRKRIKELSEDEIRTLKQKKIEETSEQEQETNSNA 133

  Fly   108 RSPPERL------HFFP------SNPEMRKAWMEICRLTVDNKWLFICGRHFRRTYLPNKGNLRK 160
            ::|...:      :..|      .|.|..|:..||         |.:.|:.    .:|..|: ..
  Rat   134 QNPSAEVGNQQDGNVLPLTLEEKENKEYLKSLFEI---------LILMGKQ----NIPLDGH-EA 184

  Fly   161 DAIPEFHLGTEEEDPLGKSIKSMKSCANRSNISFKSEDSGIDEESFKESKPHNNPCAN---CLDL 222
            |.|||   |....|    :.:::..|  |.|       ||  ||..:  |.......|   |...
  Rat   185 DEIPE---GLFAPD----NFQALLEC--RIN-------SG--EEVLR--KRFETTAVNTLFCSKT 229

  Fly   223 QQ----QLAAAHLRIQQLEERRQEE-----TDSDDDEEGEEEEHIFMLMK 263
            ||    ::..:.:|.:.|.|.|...     ||...|..|  |||:.:|::
  Rat   230 QQRQMLEICESCIREETLREVRDSHFFSIITDDVVDIAG--EEHLPVLVR 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14860	NP_650403.2	DM3	24..80	CDD:128933	22/72 (31%)
CG14860	NP_650403.2	DM3	114..169	CDD:128933	14/66 (21%)
Thap12	NP_001178559.1	THAP	6..86	CDD:398893	23/80 (29%)
		DUF4371	<153..326	CDD:405048	39/161 (24%)
		Dimer_Tnp_hAT	<668..725	CDD:399013
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910