DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14860 and LOC100498520

DIOPT Version :9

Sequence 1:	NP_650403.2	Gene:	CG14860 / 41803	FlyBaseID:	FBgn0038273	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	XP_031750188.1	Gene:	LOC100498520 / 100498520	-ID:	-	Length:	706	Species:	Xenopus tropicalis

Alignment Length:	291	Identity:	66/291 - (22%)
Similarity:	107/291 - (36%)	Gaps:	86/291 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RCIVTDCYKSGQQDSS-SMYKFPINPVVRQKWLDNIA-DIKDINLFNSRV-----------CRRH 58
            :|||.:|..:.|::|. :::.||.:....:.||.... |..|::.|..||           |.:|
Frog     3 KCIVKECKNTTQKNSGVTLHGFPNSLNAIKVWLIQTGNDFGDLDAFAQRVLESRSRWLYRMCSKH 67

  Fly    59 FETQCF---GKTKVFS-WAVPTLFLNTKEVVHQVSKPSRNSFIRRCSVRNCSSRSPPERLHFFPS 119
            |..|.:   ||..|.. .||||:|            |.:        |:|   |...|.|...|.
Frog    68 FSPQSYIWSGKKLVLKPDAVPTIF------------PGK--------VKN---RYVTENLRGLPP 109

  Fly   120 NPEMRKAWMEICRLTVDNKWLFICGRHFRRTYLPNKGNLRKDAIPEFHLGTEEED--PLGK---- 178
            :   ::|.:|: :..:.:......|.|....|:|...:      |. |:..|:..  |..|
Frog   110 S---KRAQVEM-QFQLHSIIKQHGGYHPTSLYVPPSSD------PP-HVTREQAQYKPGAKTTST 163

  Fly   179 -SIKSMKSCANRSNISFKSEDSGI---------DEESFKESKPHNNPCANCLDLQQQL--AAAHL 231
             :.|.|...:..::..|...|.|:         |.|::|....|..| .|...|:..:  |||
Frog   164 ATTKVMVDKSTNTDPMFGKADKGVLWPEFEYNFDGEAWKIKHDHFYP-YNRSSLRDSIKNAAA-- 225

  Fly   232 RIQQLEERRQEETDSD-----DDEEGEEEEH 257
                     :.||:.|     |.|..:...|
Frog   226 ---------EAETEQDFWYTNDYETDKNSRH 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14860	NP_650403.2	DM3	24..80	CDD:128933	21/71 (30%)
CG14860	NP_650403.2	DM3	114..169	CDD:128933	10/54 (19%)
LOC100498520	XP_031750188.1	THAP	5..91	CDD:398893	25/85 (29%)
		KRAB_A-box	274..310	CDD:143639
		C2H2 Zn finger	566..586	CDD:275368
		zf-C2H2	592..613	CDD:395048
		C2H2 Zn finger	593..613	CDD:275368
		zf-C2H2	619..641	CDD:395048
		C2H2 Zn finger	621..641	CDD:275368
		C2H2 Zn finger	649..669	CDD:275368
		C2H2 Zn finger	677..697	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910