Protein Alignment Dph2 and DPH1

DIOPT Version :10

• Sequence 1: NP_650402.1
• Gene: Dph2 / 41802
• FlyBaseID: FBgn0038272
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_012163.1
• Gene: DPH1 / 854703
• SGDID: S000001365
• Length: 425
• Species: Saccharomyces cerevisiae
• Alignment Length: 372
• Identity: 91/372 - (24%)
• Similarity: 160/372 - (43%)
• Gaps: 49/372 - (13%)

  Fly    34 IWNENHRRSSVDWIRKSGYKRVCLQFPDDYLPHSNAISVGLKELLAPEDVKVFILADTTYGSCCV 98
            :||          |||...||:.||.|:..|.:|..||..|::...   |:..::.|.:||:||:
Yeast    84 VWN----------IRKYNAKRIALQMPEGLLIYSLIISDILEQFCG---VETLVMGDVSYGACCI 135

  Fly    99 DEIAAAHVDADSVIHFGNAC--RSRAARLPVLYLYPELPLDVNVLLSKLQ-----GLRAESIDRQ 156
            |:..|..:|.|.::|:.::|  .....::.|||::..:.:..:.::..||     |.|
Yeast   136 DDFTARALDCDFIVHYAHSCLVPIDVTKIKVLYVFVTINIQEDHIIKTLQKNFPKGSR------- 193

  Fly   157 VCVYLDIGYQ---HVYGEKLKKQLSEILEPKELLLELFPP-IEAEST-----TTRETTNLER--I 210
            :..:..|.:.   |...:||       |..:|.:|.:.|| |:..|.     .|.|..:.|:  .
Yeast   194 IATFGTIQFNPAVHSVRDKL-------LNDEEHMLYIIPPQIKPLSRGEVLGCTSERLDKEQYDA 251

  Fly   211 CIFIGADNQRFANLSLTAPAAVQWHIYDGSSDSLSSKNPLTAQFIRRRYFHIEKCKDAQTLGLIV 275
            .:|||.......:..:..|....:. ||..:...:.:.....|.:..|...||..:..:..|||:
Yeast   252 MVFIGDGRFHLESAMIHNPEIPAFK-YDPYNRKFTREGYDQKQLVEVRAEAIEVARKGKVFGLIL 315

  Fly   276 ATLSAEGYLDVVTRLQTMAKGRGIKTQLISVGRINPAKLANFLEIDCFVLIGCPFNNMYDSKEYY 340
            ..|..:|.|:.|..|:......|.....|.:..:.|.|||.|.:||.||.:.||..::.....:.
Yeast   316 GALGRQGNLNTVKNLEKNLIAAGKTVVKIILSEVFPQKLAMFDQIDVFVQVACPRLSIDWGYAFN 380

  Fly   341 KPIVSVFEAEMALNPAWHMRYPEAYV-TDFKQLLPEGRSFLPFDAAD 386
            ||:::.:||.:.|..  .:.:.|.|. .|:.:....||...|..|.:
Yeast   381 KPLLTPYEASVLLKK--DVMFSEKYYPMDYYEAKGYGRGETPKHAIE 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dph2	NP_650402.1	diphth2_R	44..353	CDD:273013	81/326 (25%)
DPH1	NP_012163.1	Diphthamide_syn	99..403	CDD:460365	76/323 (24%)