Protein Alignment Dph2 and dph2

DIOPT Version :10

• Sequence 1: NP_650402.1
• Gene: Dph2 / 41802
• FlyBaseID: FBgn0038272
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_001082866.1
• Gene: dph2 / 562538
• ZFINID: ZDB-GENE-030219-100
• Length: 498
• Species: Danio rerio
• Alignment Length: 526
• Identity: 166/526 - (31%)
• Similarity: 254/526 - (48%)
• Gaps: 108/526 - (20%)

  Fly    10 AFSSSDTAALERQAE--------------VEQPVTLEQIWNENHRRSSVDWIRKSGYKRVCLQFP 60
            |||||..|.|:|...              .:.|.|...| ..||            :|:|.||||
Zfish     4 AFSSSSEAVLQRSVTSTHSFHPSGDLLLLYQTPETCRFI-TSNH------------FKKVALQFP 55

  Fly    61 DDYLPHSNAISVGLKELLAPEDVKVFILADTTYGSCCVDEIAAAHVDADSVIHFGNACRSRAARL 125
            |:.||.:..:|..:::   ....|.:||.||:||||||||:||.||.||.::|:|::|.|...||
Zfish    56 DELLPDAVRVSAEIED---KTKAKTYILGDTSYGSCCVDEVAAEHVGADCIVHYGSSCLSPCRRL 117

  Fly   126 PVLYLYPELPLDVNVLLSKLQGLRAESIDRQVCVYLDIGYQHVYGEKLKKQLSEILEPKELLLEL 190
            |:||::.:.|:||:...|..:.| ..::...:.|..|:.|.|.           |.:.:.||.::
Zfish   118 PLLYVFGKRPIDVHQCASSFKEL-YPNLQSHIIVLFDVTYSHA-----------IDDLRTLLCDV 170

  Fly   191 FPPIEAESTTTRETTNLERI---CI-------------------------------FIGADNQRF 221
            :|.:......|..:...|.|   |:                               :||.:....
Zfish   171 YPNVVVSRLKTDHSCGAELIQDSCVDLQSNDDGVIFKFGRQFRIKEGQTVNDYSIFYIGQEGLTL 235

  Fly   222 ANLSLTAPAAVQWHIYDGSSDSLSSKNPLTA----------QFIRRRYFHIEKCKDAQTLGLIVA 276
            .|..::      |     ::...||.||.|:          :.:.:||:.||:.|||..:|::|.
Zfish   236 TNFMMS------W-----NNCVFSSFNPETSTGRVESVQINKALMKRYYAIERAKDASVVGILVG 289

  Fly   277 TLSAEGYLDVVTRLQTMAKGRGIKTQLISVGRINPAKLANFLEIDCFVLIGCPFNNMYDSKEYYK 341
            ||....||.::.:|:...:..|.|:.:.::|:||..|||||||||.:||:.||.|::.||.|:|:
Zfish   290 TLGVANYLIIIEQLKDTIQRAGKKSYMFAMGKINVPKLANFLEIDIYVLVACPENSLLDSSEFYR 354

  Fly   342 PIVSVFEAEMALNPAWHMRYPEAYVTDFKQLLPEGRSFLPF-----DAADIPENDVSLVSGRLRG 401
            |:|:.||.|:|.|.  |..:...|||||::|||.|.|.:.|     .|.:....||||::|.||.
Zfish   355 PVVTPFEMELACNK--HREWTGEYVTDFRELLPGGSSHVGFPEPSQSATEEETTDVSLITGALRS 417

  Fly   402 AVNDSLET--GGDPASLALATQAKMALMTTDTGLSF-EDRTWQGLDPALGQTEPAKLQQGLSGIP 463
            ...:|.|.  ..:.:||.|..|. :.:..|:...|| ..|:||||:|.||||...|..:|..||.
Zfish   418 CSTNSSEMMHNSETSSLVLRNQT-LTVANTNAAASFLAGRSWQGLEPKLGQTPVVKAVKGQRGIA 481

  Fly   464 INYSHQ 469
            |.|..:
Zfish   482 IAYEEE 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dph2	NP_650402.1	diphth2_R	44..353	CDD:273013	106/352 (30%)
dph2	NP_001082866.1	Diphthamide_syn	54..377	CDD:460365	105/350 (30%)