Protein Alignment Dph2 and Dph1

DIOPT Version :10

• Sequence 1: NP_650402.1
• Gene: Dph2 / 41802
• FlyBaseID: FBgn0038272
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_001099279.1
• Gene: Dph1 / 287523
• RGDID: 1562694
• Length: 438
• Species: Rattus norvegicus
• Alignment Length: 386
• Identity: 87/386 - (22%)
• Similarity: 152/386 - (39%)
• Gaps: 97/386 - (25%)

  Fly    18 ALERQAEVEQPVTLEQIWNENHRRSSVDWIRKSGYKRVCLQFPDDYLPHSNAISVGLKELLAPED 82
            ||......|.|.|   ||.          |:::..|:|.||.|:..|..:..|...|:.....|
  Rat    48 ALPSNYNFEIPKT---IWR----------IQQAQAKKVALQMPEGLLLFACTIVDILERFTKAE- 98

  Fly    83 VKVFILADTTYGSCCVDEIAAAHVDADSVIHFGNAC----RSRAARLPVLYLYPELPLD------ 137
              |.::.|.|||:||||:..|..:..|.::|:|::|    .:......|||::.::.:|
  Rat    99 --VMVMGDVTYGACCVDDFTARALGVDFLVHYGHSCLVPMDTSVQDFRVLYVFVDIRIDTAHLLD 161

  Fly   138 --------------------VNVLLSKLQGLRAESIDRQVCVYLDIGYQHVYGEKLKKQLSEILE 182
                                |:.|.:..|.|:|:              .|:...:.|.     |.
  Rat   162 SVRLTFTPGSSLALVSTIQFVSTLQAAAQELKAD--------------YHISVPQCKP-----LS 207

  Fly   183 PKELLLELFPPIEAESTTTRETTNLERICIFIGADNQRFANLSLTAPAAVQWHIYDGSSDSLSSK 247
            |.|:|         ..|:.|....:|.: :::|.......::.:..|....:. ||..|..||
  Rat   208 PGEIL---------GCTSPRLPKEVEAV-VYLGDGRFHLESVMIANPNIPSYR-YDPYSKVLS-- 259

  Fly   248 NPLTAQFIRRRYFH----------IEKCKDAQTLGLIVATLSAEGYLDVVTRLQTMAKGRGIKTQ 302
                    |..|.|          |...:.|:..|||:.||..:|...|:..|::..:..|:...
  Rat   260 --------REYYDHQRMQATRQEAIAAARSAKFWGLILGTLGRQGSPKVLEHLESQLRNLGLPFL 316

  Fly   303 LISVGRINPAKLANFLEIDCFVLIGCPFNNMYDSKEYYKPIVSVFEAEMALNP-AWHMRYP 362
            .:.:..|.|:||:....:|.:|.:.||..::.....:.||:::.:||.:||.. :|...||
  Rat   317 RLLLSEIFPSKLSLLPSVDVWVQVACPRLSIDWGSAFPKPLLTPYEAAVALKEISWQQPYP 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dph2	NP_650402.1	diphth2_R	44..353	CDD:273013	75/348 (22%)
Dph1	NP_001099279.1	Diphthamide_syn	76..377	CDD:460365	73/343 (21%)