Protein Alignment Dph2 and dph-2

DIOPT Version :10

• Sequence 1: NP_650402.1
• Gene: Dph2 / 41802
• FlyBaseID: FBgn0038272
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_001254257.1
• Gene: dph-2 / 174649
• WormBaseID: WBGene00007488
• Length: 476
• Species: Caenorhabditis elegans
• Alignment Length: 502
• Identity: 154/502 - (30%)
• Similarity: 253/502 - (50%)
• Gaps: 67/502 - (13%)

  Fly     4 SETSASAFSSSDTAALERQAEVEQPVT--LEQI-WNENHRRSSVD----WIRKSGYKRVCLQFPD 61
            :|::.|||.::.|.| :...|.|...|  .|.: .|:.|....:|    ||::..::|:.|||||
 Worm     2 TESAPSAFFTTSTPA-DHVHEEESSNTGYFENLPENDIHSFFEIDATSEWIKQGNHQRIALQFPD 65

  Fly    62 DYLPHSNAISVGLKELLAPEDV-KVFILADTTYGSCCVDEIAAAHVDADSVIHFGNACRSRAA-R 124
            ..||:|..::..::.....|.. |.|:||||:|.||||||:||||.|..:::|||.||.|... :
 Worm    66 SLLPYSEKVTKLIESRFRSESAKKTFVLADTSYRSCCVDEVAAAHADCTALVHFGEACHSAPTDK 130

  Fly   125 LPVLYLYPELPLDVNVLLSKLQGLRAESIDRQVCVYLDIGYQHVYGEKLKKQLSEILEPKELLLE 189
            :.|.|:...:|:.::....:.|.:..:.....:.:.:|..:.|.. ||:...:.|:|....
 Worm   131 IDVKYVLGSMPIFIDQFRMEFQNVADQLTAEHIVLLMDSCFSHEQ-EKVAAVIKEVLPGNR---- 190

  Fly   190 LFPPIEAESTTTRETTNLERICIFIGAD-------NQ-------RFANLSLTAPAAVQWHIYDGS 240
               .:|.....:.:.....|..|::|.:       ||       .|.|    :|....|.:...|
 Worm   191 ---HVECSLLPSEDVLKQNRQNIYLGREIPSCLRNNQPTDLIFCGFPN----SPLLPIWLLSYPS 248

  Fly   241 SDSLSSKNPL----------TAQFIRRRYFHIEKCKDAQTLGLIVATLSAEGYLDVVTRLQTMAK 295
            ..::|..||:          :::.:|:|.|.:||.|||.|:||:|.::..:.:.:.|.|::.|.|
 Worm   249 CSTVSHFNPINKTIQHESTRSSRLLRKRLFLVEKLKDADTVGLVVGSVGVDKHREAVKRMREMCK 313

  Fly   296 GRGIKTQLISVGRINPAKLANF-LEIDCFVLIGCPFNNMYDSKEYYKPIVSVFEAEMALNPA--W 357
            ..|.|..:||||:||..||:|| .:||.|||:.|||..:.||.:|::|:||.||||:|||||  |
 Worm   314 KAGKKIYVISVGKINVPKLSNFSTDIDVFVLLSCPFGVVLDSSDYFRPVVSYFEAEIALNPAKTW 378

  Fly   358 HMRYPEAYVTDFKQLLPEG-RSFLPFDAADIPENDVSLVSGRLRGAVNDSLETGGDPASLALATQ 421
            ...:  .:..:|...|.:. .:.:|.|.|   ..|.||:||::|....:..:.|..|:|:|:...
 Worm   379 AADF--GWSAEFAAFLEDKIETEVPDDKA---AGDFSLISGKVRVQKTEEEKNGDGPSSVAIYNP 438

  Fly   422 AKMALMTTDTGLSFEDRTWQGLDPALGQTEPA-KLQQGLSGIPINYS 467
            ...           .||||:||:..:...|.: |:.:|.|||...||
 Worm   439 GYC-----------NDRTWKGLNDGVSTAEDSTKMGEGRSGIAQGYS 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dph2	NP_650402.1	diphth2_R	44..353	CDD:273013	107/339 (32%)
dph-2	NP_001254257.1	diphth2_R	6..476	CDD:473165	153/498 (31%)