Protein Alignment CycC and CCNL2

DIOPT Version :9

• Sequence 1: NP_476848.1
• Gene: CycC / 41801
• FlyBaseID: FBgn0004597
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: XP_011540518.1
• Gene: CCNL2 / 81669
• HGNCID: 20570
• Length: 553
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 64/280 - (22%)
• Similarity: 115/280 - (41%)
• Gaps: 62/280 - (22%)

  Fly    32 LNEDEYQKVFIFFANVIQVLGEQLKLRQQVIATATVYFKR-FYARNSLK-NIDP-LLLAPT---- 89
            |:.|....:.:....:||..|..|:|.|..:||..|.|:| ||.::.:| :::| .|..|:
Human    69 LDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEPSSLWRPSGRRG 133

  Fly    90 --------------------------------------CILLASKVEEFGVISNSRLISICQSAI 116
                                                  |:...|..|        |..::|..:.
Human   134 WGQTWACCNASASACVNGLCPPGFQDRRGPKTHTGRHQCVSPPSTAE--------RQKTLCSLSG 190

  Fly   117 KTKFSYAYAQEFPYRTNHILECEFYLLENLDCCLIVYQPYRPLLQLVQ--DMGQEDQLLTLSWRI 179
            :........|::....|.|::.|..:|:.|..|:.|..|::.::..:|  :..:...|:..||..
Human   191 RKPVPLLLDQDYVNLKNQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSWNY 255

  Fly   180 VNDSLRTDVCLLYPPYQIAIACLQIACVILQKDATKQ--WFAELNVDLDKVQEIVRAIVNLYELW 242
            :||||||||.:.:.|..||.||:.:|...|:.....:  ||.......:::|||...|:.||.
Human   256 MNDSLRTDVFVRFQPESIACACIYLAARTLEIPLPNRPHWFLLFGATEEEIQEICLKILQLYA-- 318

  Fly   243 KDWKEKDEIQMLLSKIPKPK 262
               ::|.::..|..::.|.|
Human   319 ---RKKVDLTHLEGEVEKRK 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycC	NP_476848.1	CYCLIN_CCNC_rpt1	40..146	CDD:410217	27/150 (18%)
		CYCLIN_CCNC_rpt2	154..245	CDD:410218	28/94 (30%)
CCNL2	XP_011540518.1	CCL1	69..>306	CDD:227640	54/244 (22%)
		CYCLIN	233..315	CDD:214641	25/81 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5333
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810