DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycC and ccnl1b

DIOPT Version :9

Sequence 1:	NP_476848.1	Gene:	CycC / 41801	FlyBaseID:	FBgn0004597	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	NP_956034.1	Gene:	ccnl1b / 326088	ZFINID:	ZDB-GENE-030131-4813	Length:	498	Species:	Danio rerio

Alignment Length:	235	Identity:	61/235 - (25%)
Similarity:	104/235 - (44%)	Gaps:	38/235 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 IQVLGEQLKLRQQVIATATVYFKRFYARNSLKNIDPLLLAPTCILLASKVEEF------------ 100
            ||..|..|:|.|..:||..|.|:||:...|....:..::|..|:.||||:||.
Zfish    70 IQSAGILLRLPQVAMATGQVIFQRFFFSKSFVKHNFEIVAMACVNLASKIEESPRRVRDVINVFH 134

  Fly   101 ----GVISNSRLISICQSAIKTKFSYAYAQEFPYRTNHILECEFYLLENLDCCLIVYQPYRPLLQ 161
                |....|..:.:.|:.|.||             |.:::.|..:|:.|..|:.|..|::.::.
Zfish   135 HLKQGKGKKSTPLILDQNYINTK-------------NQVIKAERRILKELGFCVHVKHPHKIIVM 186

  Fly   162 LVQ--DMGQEDQLLTLSWRIVNDSLRTDVCLLYPPYQIAIACLQIACVILQ--KDATKQWFAELN 222
            .:|  :..:...|:..:|..:||:|||...:.:.|..||.||:.:|..:||  ..:...||....
Zfish   187 YLQVLECEKNQMLVQTAWNYMNDALRTSAFVRFEPETIACACIYLAARVLQIPLPSKPHWFLLFG 251

  Fly   223 VDLDKVQEIVRAIVNLYELWKDWKEKDEIQMLLSKIPKPK 262
            ...:.::||....:.||.     :||...:.|..::.|.|
Zfish   252 ATKEDIKEICINTMKLYS-----REKPHSEQLERQVEKRK 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycC	NP_476848.1	CYCLIN_CCNC_rpt1	40..146	CDD:410217	30/113 (27%)
CycC	NP_476848.1	CYCLIN_CCNC_rpt2	154..245	CDD:410218	23/94 (24%)
ccnl1b	NP_956034.1	CYCLIN	62..134	CDD:238003	21/63 (33%)
		Cyclin-like 1	68..169		29/111 (26%)
		Cyclin-like 2	182..266		20/83 (24%)
		CYCLIN	184..260	CDD:214641	18/75 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	294..498
		RS	366..396
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5333
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810