Protein Alignment CycC and cic-1

DIOPT Version :10

• Sequence 1: NP_476848.1
• Gene: CycC / 41801
• FlyBaseID: FBgn0004597
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_497548.2
• Gene: cic-1 / 175357
• WormBaseID: WBGene00000506
• Length: 302
• Species: Caenorhabditis elegans
• Alignment Length: 293
• Identity: 107/293 - (36%)
• Similarity: 173/293 - (59%)
• Gaps: 27/293 - (9%)

  Fly     1 MAGNFWQSSHSQQWILDKPDLLRERQHDLLALNEDEYQKVFIFFANVIQVLGEQ---------LK 56
            ||.|||:|||.||||.||.::.::|..|:...||:||.::.||:||.|..:..:         .|
 Worm     1 MALNFWKSSHCQQWIFDKTEIWKQRAEDMKIYNEEEYNRLNIFWANFITAVATEGAHSQANVGCK 65

  Fly    57 LRQQVIATATVYFKRFYARNSLKNIDPLLLAPTCILLASKVEEFGVISNSRLISICQSAIKTKFS 121
            |||||||||.:||||||.|.|.:::.|.|:|.|.:.||.||||...:|.|..:......:..::.
 Worm    66 LRQQVIATAIIYFKRFYLRQSFRDMCPFLVASTALFLACKVEEHTTLSVSSFLKNTAIVLPKRWG 130

  Fly   122 YAYAQEFPYRTNHILECEFYLLENLDCCLIVYQPYRPLLQLVQDMGQEDQLLTLS---------- 176
            ..: :....:...:.:.||.|:|.|||||:|:...||:.:|::|:.|..|..|::
 Worm   131 VTF-ETTSTKNGVVYDSEFILVEILDCCLVVHHASRPMFELLEDLKQFTQQSTIANQPIKDLEAI 194

  Fly   177 ----WRIVNDSLRTDVCLLYPPYQIAIACLQIACVILQK-DATKQWFAELNVDLDKVQEIVRAIV 236
                .::.|||||.||.|::||:.|.::.:.:|..::.: :..:.|..|::.|.:||.:.|..|.
 Worm   195 EAQCQKVANDSLRCDVSLIFPPHVIGLSSIMVAMELMGRGEELEAWLVEVDTDFEKVTDCVEQIY 259

  Fly   237 NLYELWKDWKEKDEIQMLLSKIPKP--KPPPQR 267
            .:|.|||.:.||:|::.|::|:|||  :||||:
 Worm   260 KMYTLWKSFDEKEEVKKLMAKLPKPNQQPPPQQ 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycC	NP_476848.1	CYCLIN_CCNC_rpt1	40..146	CDD:410217	39/114 (34%)
		CYCLIN_CCNC_rpt2	154..245	CDD:410218	30/105 (29%)
cic-1	NP_497548.2	ccl1	8..281	CDD:129660	94/273 (34%)
		CYCLIN_CCNC_rpt1	40..154	CDD:410217	39/114 (34%)