DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycC and Ccnc

DIOPT Version :9

Sequence 1:	NP_476848.1	Gene:	CycC / 41801	FlyBaseID:	FBgn0004597	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	NP_001093942.1	Gene:	Ccnc / 114839	RGDID:	70905	Length:	283	Species:	Rattus norvegicus

Alignment Length:	265	Identity:	192/265 - (72%)
Similarity:	228/265 - (86%)	Gaps:	1/265 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAGNFWQSSHSQQWILDKPDLLRERQHDLLALNEDEYQKVFIFFANVIQVLGEQLKLRQQVIATA 65
            ||||||||||..||||||.|||:|||.||..|:|:||.|:.|||.||||.|||.|||||||||||
  Rat     1 MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQVIATA 65

  Fly    66 TVYFKRFYARNSLKNIDPLLLAPTCILLASKVEEFGVISNSRLISICQSAIKTKFSYAYAQEFPY 130
            ||||||||||.|||:|||:|:||||:.||||||||||:||:|||:...|.:||:||||:.:||||
  Rat    66 TVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAATTSVLKTRFSYAFPKEFPY 130

  Fly   131 RTNHILECEFYLLENLDCCLIVYQPYRPLLQLVQDMGQEDQLLTLSWRIVNDSLRTDVCLLYPPY 195
            |.||||||||||||.:|||||||.|||||||.||||||||.||.|:||||||:.|||:||||||:
  Rat   131 RMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDVLLPLAWRIVNDTYRTDLCLLYPPF 195

  Fly   196 QIAIACLQIACVILQKDATKQWFAELNVDLDKVQEIVRAIVNLYELWKDWKEKDEIQMLLSKIPK 260
            .||:|||.:|||:.|||| :||||||:||::|:.||:|.|:.|||.||::.|:.|:..:|||:||
  Rat   196 MIALACLHVACVVQQKDA-RQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKMPK 259

  Fly   261 PKPPP 265
            |||||
  Rat   260 PKPPP 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycC	NP_476848.1	CYCLIN_CCNC_rpt1	40..146	CDD:410217	81/105 (77%)
CycC	NP_476848.1	CYCLIN_CCNC_rpt2	154..245	CDD:410218	63/90 (70%)
Ccnc	NP_001093942.1	CYCLIN_CCNC_rpt1	40..146	CDD:410217	81/105 (77%)
Ccnc	NP_001093942.1	CYCLIN_CCNC_rpt2	154..245	CDD:410218	63/91 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	170	1.000	Domainoid score	I3691
eggNOG	1	0.900	-	-		E1_COG5333
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3803
Inparanoid	1	1.050	389	1.000	Inparanoid score	I1935
OMA	1	1.010	-	-		QHG55499
OrthoDB	1	1.010	-	-		D1079428at2759
OrthoFinder	1	1.000	-	-		FOG0003755
OrthoInspector	1	1.000	-	-		oto98637
orthoMCL	1	0.900	-	-		OOG6_103590
Panther	1	1.100	-	-	LDO	PTHR10026
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2616
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.880