DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycC and Ccnl1

DIOPT Version :9

Sequence 1:	NP_476848.1	Gene:	CycC / 41801	FlyBaseID:	FBgn0004597	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	NP_446114.1	Gene:	Ccnl1 / 114121	RGDID:	620864	Length:	527	Species:	Rattus norvegicus

Alignment Length:	243	Identity:	67/243 - (27%)
Similarity:	108/243 - (44%)	Gaps:	41/243 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 IFFANVIQVLGEQLKLRQQVIATATVYFKRFYARNSLKNIDPLLLAPTCILLASKVEEF------ 100
            |....:||..|..|:|.|..:||..|.|.||:...|.......::|..||.||||:||.
  Rat    85 ILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACINLASKIEEAPRRIRD 149

  Fly   101 ------------GVISNSRLISICQSAIKTKFSYAYAQEFPYRTNHILECEFYLLENLDCCLIVY 153
                        |..:.|.|| :.|:.|.||             |.:::.|..:|:.|..|:.|.
  Rat   150 VINVFHHLRQLRGKRTPSPLI-LDQNYINTK-------------NQVIKAERRVLKELGFCVHVK 200

  Fly   154 QPYRPLLQLVQ--DMGQEDQLLTLSWRIVNDSLRTDVCLLYPPYQIAIACLQIACVILQ--KDAT 214
            .|::.::..:|  :..:...|:..:|..:||||||:|.:.:.|..||.||:.:|...||  ....
  Rat   201 HPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVFVRFQPETIACACIYLAARALQIPLPTR 265

  Fly   215 KQWFAELNVDLDKVQEIVRAIVNLYELWKDWKEKDEIQMLLSKIPKPK 262
            ..||.......:::|||....:.||.     ::|...::|..::.|.|
  Rat   266 PHWFLLFGTTEEEIQEICIETLRLYT-----RKKPNYELLEKEVEKRK 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycC	NP_476848.1	CYCLIN_CCNC_rpt1	40..146	CDD:410217	34/121 (28%)
CycC	NP_476848.1	CYCLIN_CCNC_rpt2	154..245	CDD:410218	26/94 (28%)
Ccnl1	NP_446114.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..37
		CYCLIN_SF	41..196	CDD:424085	35/124 (28%)
		Cyclin-like 1	89..191		32/115 (28%)
		CYCLIN_SF	200..322	CDD:424085	30/114 (26%)
		Cyclin-like 2	204..288		23/83 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	327..527
		RS	391..433
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5333
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810