DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment UQCR-C1 and Pmpcb

DIOPT Version :9

Sequence 1:	NP_650401.1	Gene:	UQCR-C1 / 41800	FlyBaseID:	FBgn0038271	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_071790.1	Gene:	Pmpcb / 64198	RGDID:	621297	Length:	489	Species:	Rattus norvegicus

Alignment Length:	454	Identity:	316/454 - (69%)
Similarity:	364/454 - (80%)	Gaps:	14/454 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 RYKSAATLQKTLLNIPATQVTKLDNGLRVASEDSGASTATVGLWIDAGSRSENEKNNGVAHFLEH 88
            |.:|.....:.:||:|.||||.|:||||||||:||.||.|||||||||||.|||||||.||||||
  Rat    41 RLRSTQAAPQVVLNVPETQVTCLENGLRVASENSGISTCTVGLWIDAGSRYENEKNNGTAHFLEH 105

  Fly    89 MAFKGTAKRSQTDLELEVENLGAHLNAYTSREQTVFYAKCLSKDVPKAVEILADIIQNSKLGEAE 153
            ||||||.||||.|||||:||:||||||||||||||:|||..|||:|:||||||||||||.|||||
  Rat   106 MAFKGTKKRSQLDLELEIENMGAHLNAYTSREQTVYYAKAFSKDLPRAVEILADIIQNSTLGEAE 170

  Fly   154 IARERSVILREMQEVESNLQEVVFDHLHATAYQGTPLGQTILGPTKNIQSIGKADLTDYIQTHYK 218
            |.|||.||||||||||:||||||||:|||||||.|.||:||||||:||:||.:.||.|||.||||
  Rat   171 IERERGVILREMQEVETNLQEVVFDYLHATAYQNTALGRTILGPTENIKSISRKDLVDYITTHYK 235

  Fly   219 ASRIVLAAAGGVKHDDLVKLA--------CSSLGGLEASVLPAEVTPCRFTGSEVRVRDDSLPLA 275
            ..||||||||||.|::|::||        |:..|.:.|  ||    ||:|||||:|||||.:|||
  Rat   236 GPRIVLAAAGGVCHNELLELAKFHFGDSLCAHKGDVPA--LP----PCKFTGSEIRVRDDKMPLA 294

  Fly   276 HVAIAVEGCGWTDQDNIPLMVANTLVGAWDRSQGGGANNASNLARASAEDNLCHSFQSFNTCYKD 340
            |:|:|:|..|||..|.|.|||||||:|.||||.|||.|.:|.||:.:...|||||||||||.|.|
  Rat   295 HLAVAIEAVGWTHPDTIRLMVANTLIGNWDRSFGGGMNLSSKLAQLTCHGNLCHSFQSFNTSYTD 359

  Fly   341 TGLWGIYFVCDPLQCEDMLFNVQTEWMRLCTMVTEAEVERAKNLLKTNMLLQLDGTTPICEDIGR 405
            |||||:|.||:.....|||..||.|||||||.|:|:||.||||||||||||||||:|||||||||
  Rat   360 TGLWGLYMVCEQATVADMLHAVQKEWMRLCTAVSESEVARAKNLLKTNMLLQLDGSTPICEDIGR 424

  Fly   406 QILCYNRRIPLHELEQRIDAVSVGNVRDVAMKYIYDRCPAVAAVGPVENLPDYNRIRSSMYWLR 469
            |:||||||||:.|||.|||||....||:|..||||.:.||:||:||:|.|||:|:|.|:|.|.|
  Rat   425 QMLCYNRRIPIPELEARIDAVDAEMVREVCTKYIYGKSPAIAALGPIERLPDFNQICSNMRWTR 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
UQCR-C1	NP_650401.1	PqqL	35..459	CDD:223685	308/431 (71%)
Pmpcb	NP_071790.1	PqqL	46..478	CDD:223685	308/437 (70%)
		Peptidase_M16	68..215	CDD:279066	124/146 (85%)
		Peptidase_M16_C	220..404	CDD:282978	114/189 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339321
Domainoid	1	1.000	250	1.000	Domainoid score	I2055
eggNOG	1	0.900	-	-		E1_COG0612
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3160
Inparanoid	1	1.050	628	1.000	Inparanoid score	I813
OMA	1	1.010	-	-		QHG53495
OrthoDB	1	1.010	-	-		D287307at33208
OrthoFinder	1	1.000	-	-		FOG0001232
OrthoInspector	1	1.000	-	-		oto97463
orthoMCL	1	0.900	-	-		OOG6_100777
Panther	1	1.100	-	-	LDO	PTHR11851
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X964
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770