DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment UQCR-C1 and uqcrc1

DIOPT Version :9

Sequence 1:	NP_650401.1	Gene:	UQCR-C1 / 41800	FlyBaseID:	FBgn0038271	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_001016710.1	Gene:	uqcrc1 / 549464	XenbaseID:	XB-GENE-5905304	Length:	478	Species:	Xenopus tropicalis

Alignment Length:	451	Identity:	273/451 - (60%)
Similarity:	341/451 - (75%)	Gaps:	5/451 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 KRYKSAATLQKTLLNIPATQVTKLDNGLRVASEDSGASTATVGLWIDAGSRSENEKNNGVAHFLE 87
            :|..||....:.:.|||.||::.|.||||||||:||.:|.|||:||..|||.||:||||..:|||
Frog    28 QRNGSAVPYARAVQNIPETQISSLANGLRVASEESGQATCTVGVWIGTGSRYENDKNNGAGYFLE 92

  Fly    88 HMAFKGTAKRSQTDLELEVENLGAHLNAYTSREQTVFYAKCLSKDVPKAVEILADIIQNSKLGEA 152
            |:|||||.||.|..||.|||:|||||||||:||||..|.|..|:|:|||||||||::||..|.::
Frog    93 HLAFKGTKKRPQAALEQEVESLGAHLNAYTTREQTAIYIKAQSQDLPKAVEILADVVQNCSLEDS 157

  Fly   153 EIARERSVILREMQEVESNLQEVVFDHLHATAYQGTPLGQTILGPTKNIQSIGKADLTDYIQTHY 217
            :|.:||.||||||||::|||||||||:|||||||||.||:|::||::|.:.:.:|||.||:.:|:
Frog   158 QIEKERHVILREMQEIDSNLQEVVFDYLHATAYQGTALGRTVVGPSENARRLNRADLVDYVSSHF 222

  Fly   218 KASRIVLAAAGGVKHDDLVKLACSSLGGL----EASVLPAEVTPCRFTGSEVRVRDDSLPLAHVA 278
            ||.|:||||||||.|.:|..||.....||    |...:|. :.||||||||:|.|:|.|||||:|
Frog   223 KAPRMVLAAAGGVNHKELCDLAQRHFSGLSYEYEKDAVPL-LPPCRFTGSEIRARNDDLPLAHLA 286

  Fly   279 IAVEGCGWTDQDNIPLMVANTLVGAWDRSQGGGANNASNLARASAEDNLCHSFQSFNTCYKDTGL 343
            |||||.||...|||||:|||.:||::..:.|||.|.:|.:|..:||..||.|||.|:..|.||||
Frog   287 IAVEGPGWNSSDNIPLLVANAIVGSYHVTYGGGKNLSSRVASVAAEHKLCQSFQPFHIRYSDTGL 351

  Fly   344 WGIYFVCDPLQCEDMLFNVQTEWMRLCTMVTEAEVERAKNLLKTNMLLQLDGTTPICEDIGRQIL 408
            :|::||.|....||||...|.|||||||.||::||.:|||.|||.:|.|||||||:|||||||:|
Frog   352 FGLHFVTDRHNIEDMLHIAQGEWMRLCTGVTDSEVAQAKNALKTALLAQLDGTTPVCEDIGRQVL 416

  Fly   409 CYNRRIPLHELEQRIDAVSVGNVRDVAMKYIYDRCPAVAAVGPVENLPDYNRIRSSMYWLR 469
            ...:||.|.||..||||||...|.::..||:||:|||||.|||:|.:||||||||:|||||
Frog   417 TLGQRISLEELNARIDAVSAKKVSEICSKYLYDKCPAVAGVGPIEQIPDYNRIRSAMYWLR 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
UQCR-C1	NP_650401.1	PqqL	35..459	CDD:223685	259/427 (61%)
uqcrc1	NP_001016710.1	PqqL	37..467	CDD:223685	259/430 (60%)
		Peptidase_M16	56..203	CDD:279066	101/146 (69%)
		Peptidase_M16_C	208..393	CDD:282978	101/185 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53495
OrthoDB	1	1.010	-	-		D287307at33208
OrthoFinder	1	1.000	-	-		FOG0001232
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11851
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X964
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.030