DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment UQCR-C1 and uqcrc1

DIOPT Version :9

Sequence 1:	NP_650401.1	Gene:	UQCR-C1 / 41800	FlyBaseID:	FBgn0038271	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_957114.1	Gene:	uqcrc1 / 393793	ZFINID:	ZDB-GENE-040426-1792	Length:	474	Species:	Danio rerio

Alignment Length:	452	Identity:	253/452 - (55%)
Similarity:	344/452 - (76%)	Gaps:	5/452 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 IKRYKSAATLQKTLLNIPATQVTKLDNGLRVASEDSGASTATVGLWIDAGSRSENEKNNGVAHFL 86
            ::|.:::.:..::||..|.|::|.||||||:|||::...|.||||||..|||.|.|||||...||
Zfish    23 LRRGQASVSYAQSLLGAPETRLTTLDNGLRIASEETNQPTCTVGLWIGCGSRFETEKNNGAGFFL 87

  Fly    87 EHMAFKGTAKRSQTDLELEVENLGAHLNAYTSREQTVFYAKCLSKDVPKAVEILADIIQNSKLGE 151
            ||||||||.|..|:.||..||::|.|||||||||.|.:|.|.||||:|||||:||:::|:..|.|
Zfish    88 EHMAFKGTKKHPQSALEQAVESMGGHLNAYTSREHTAYYMKTLSKDLPKAVELLAEVVQSLSLSE 152

  Fly   152 AEIARERSVILREMQEVESNLQEVVFDHLHATAYQGTPLGQTILGPTKNIQSIGKADLTDYIQTH 216
            ||:.::|:|.|||::|:|.:||:|..|.|||||:|||.|..::.||:.||:::.:.||.:||..|
Zfish   153 AEMEQQRTVALRELEEIEGSLQDVCLDLLHATAFQGTALSHSVFGPSANIRTLTRNDLLEYINCH 217

  Fly   217 YKASRIVLAAAGGVKHDDLVKLACSSLGGL----EASVLPAEVTPCRFTGSEVRVRDDSLPLAHV 277
            :||.|:|||.||||.||::|.||...|||:    |...:|. ::||||||||:|:|||::||||:
Zfish   218 FKAPRMVLATAGGVSHDEVVSLAKQHLGGISFEYEGDAVPV-LSPCRFTGSEIRMRDDAMPLAHI 281

  Fly   278 AIAVEGCGWTDQDNIPLMVANTLVGAWDRSQGGGANNASNLARASAEDNLCHSFQSFNTCYKDTG 342
            ||||||.|....|.:||||||:::|::|.:.|||.:.:|.||:.:||.|||||||:|.:.|.|||
Zfish   282 AIAVEGPGAASPDIVPLMVANSIIGSYDITFGGGKHLSSRLAQRAAELNLCHSFQTFYSSYSDTG 346

  Fly   343 LWGIYFVCDPLQCEDMLFNVQTEWMRLCTMVTEAEVERAKNLLKTNMLLQLDGTTPICEDIGRQI 407
            |.|||||.:.|:.|||:...|..|:.:||.|||::|.||||.|:.:::.||:||||:|::|||.|
Zfish   347 LLGIYFVTEKLKIEDMMHWAQNAWINVCTTVTESDVARAKNALRASLVGQLNGTTPVCDEIGRHI 411

  Fly   408 LCYNRRIPLHELEQRIDAVSVGNVRDVAMKYIYDRCPAVAAVGPVENLPDYNRIRSSMYWLR 469
            |.|.|||||.|.:.||:||:...||||..|||||:||||:||||:|.||||||:||:|:|||
Zfish   412 LNYGRRIPLAEWDARIEAVTPSVVRDVCSKYIYDKCPAVSAVGPIEQLPDYNRMRSAMFWLR 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
UQCR-C1	NP_650401.1	PqqL	35..459	CDD:223685	243/427 (57%)
uqcrc1	NP_957114.1	PqqL	39..463	CDD:223685	241/424 (57%)
		Peptidase_M16	52..199	CDD:279066	86/146 (59%)
		Peptidase_M16_C	204..389	CDD:282978	99/185 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53495
OrthoDB	1	1.010	-	-		D287307at33208
OrthoFinder	1	1.000	-	-		FOG0001232
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100777
Panther	1	1.100	-	-	O	PTHR11851
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X964
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.930