DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment UQCR-C1 and Pmpca

DIOPT Version :9

Sequence 1:	NP_650401.1	Gene:	UQCR-C1 / 41800	FlyBaseID:	FBgn0038271	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	XP_038960652.1	Gene:	Pmpca / 296588	RGDID:	727897	Length:	538	Species:	Rattus norvegicus

Alignment Length:	489	Identity:	143/489 - (29%)
Similarity:	255/489 - (52%)	Gaps:	55/489 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 KRYKSAAT-----LQKTLLNIP-------------ATQVTKLDNGLRVASEDSGASTATVGLWID 69
            :|:.|.||     |...|..:|             .|:||.|||||||||::......|:|:.|:
  Rat    44 RRFSSGATYPNIPLSSPLPGVPKPIFATVDGQEKFETKVTTLDNGLRVASQNKFGQFCTLGILIN 108

  Fly    70 AGSRSENEKNNGVAHFLEHMAFKGTAK-RSQTDLELEVENLGAHLNAYTSREQTVFYAKCLSKDV 133
            :|||.|.:..:|:|||||.:||..||: .|:.::.|.:|..|...:..|||:.|::.....||.:
  Rat   109 SGSRYEAKYLSGIAHFLEKLAFSSTARFDSKDEILLTLEKHGGICDCQTSRDTTMYAVSADSKGL 173

  Fly   134 PKAVEILADIIQNSKLGEAEIARERSVILREMQE--VESNLQEVVFDHLHATAYQGTPLGQTILG 196
            ...|.:|||::.:.:|.:.||...|..:..|:::  :..:.:.::.:.:|..|::...:|.....
  Rat   174 DTVVGLLADVVLHPRLTDEEIEMTRMAVQFELEDLNMRPDPEPLLTEMIHEAAFRENTVGLHRFC 238

  Fly   197 PTKNIQSIGKADLTDYIQTHYKASRIVLAAAGGVKHDDLVKLACSSLGGLEAS-----VLPAEVT 256
            |.:||..|.:..|..|::.:|...|:|||.. ||:|:.||:.|...|.|::.:     .:..:.:
  Rat   239 PVENIGKIDREVLHSYLKNYYTPDRMVLAGV-GVEHEHLVECARKYLLGVQPAWGAPGAVDVDSS 302

  Fly   257 PCRFTGSEVRVRDD---------SLP-LAHVAIAVEGCGWTDQDNIPLMVANTLVGAWDRSQGGG 311
            ..::||..::|..|         .:| |.|:.:.:|.|.:.::|.||..|.|.::|      |||
  Rat   303 VAQYTGGIIKVERDMSNVSLGPTPIPELTHIMVGLESCSFLEEDFIPFAVLNMMMG------GGG 361

  Fly   312 ANNASNLARAS---------AEDNLCHSFQSFNTCYKDTGLWGIYFVCDPLQCEDMLFNVQTEWM 367
            :.:|....:..         ...:..::..|::..|:||||..|:...||.|..:|:..:..|::
  Rat   362 SFSAGGPGKGMFSRLYLNVLNRHHWMYNATSYHHSYEDTGLLCIHASADPRQVREMVEIITKEFI 426

  Fly   368 RLCTMVTEAEVERAKNLLKTNMLLQLDGTTPICEDIGRQILC-YNRRIPLHELEQRIDAVSVGNV 431
            .:...|...|:||||..|.:.:::.|:....|.||:|||:|. ::|::| |||...|..|...::
  Rat   427 LMGRTVDLVELERAKTQLMSMLMMNLESRPVIFEDVGRQVLATHSRKLP-HELCTLIRNVKPEDI 490

  Fly   432 RDVAMKYIYDRCPAVAAVGPVENLPDYNRIRSSM 465
            :.||.|.:..: |||||:|.:.:||.|..|::::
  Rat   491 KRVASKMLRGK-PAVAALGDLTDLPTYEHIQAAL 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
UQCR-C1	NP_650401.1	PqqL	35..459	CDD:223685	136/464 (29%)
Pmpca	XP_038960652.1	PqqL	78..517	CDD:223685	134/447 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0612
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810