Protein Alignment UQCR-C1 and PMPCA

DIOPT Version :10

• Sequence 1: NP_650401.1
• Gene: UQCR-C1 / 41800
• FlyBaseID: FBgn0038271
• Length: 470
• Species: Drosophila melanogaster
• Sequence 2: XP_005266116.1
• Gene: PMPCA / 23203
• HGNCID: 18667
• Length: 563
• Species: Homo sapiens
• Alignment Length: 475
• Identity: 139/475 - (29%)
• Similarity: 236/475 - (49%)
• Gaps: 66/475 - (13%)

  Fly     1 MALRVLGVTQNMR-------SFMR-GVDMIKRYKSAAT-----LQKTLLNIP------------- 39
            ||..||..|:.:|       |.:| |....:|:.|...     |...|..:|
Human     1 MAAVVLAATRLLRGSGSWGCSRLRFGPPAYRRFSSGGAYPNIPLSSPLPGVPKPVFATVDGQEKF 65

  Fly    40 ATQVTKLDNGLRVASEDSGASTATVGLWIDAGSRSENEKNNGVAHFLEHMAFKGTAK-RSQTDLE 103
            .|:||.|||||||||::......|||:.|::|||.|.:..:|:|||||.:||..||: .|:.::.
Human    66 ETKVTTLDNGLRVASQNKFGQFCTVGILINSGSRYEAKYLSGIAHFLEKLAFSSTARFDSKDEIL 130

  Fly   104 LEVENLGAHLNAYTSREQTVFYAKCLSKDVPKAVEILADIIQNSKLGEAEIARERSVILREMQEV 168
            |.:|..|...:..|||:.|::.....||.:...|.:|||::...:|.:.|:...|..:..|::::
Human   131 LTLEKHGGICDCQTSRDTTMYAVSADSKGLDTVVALLADVVLQPRLTDEEVEMTRMAVQFELEDL 195

  Fly   169 ESNL----QEVVFDHLHATAYQGTPLGQTILGPTKNIQSIGKADLTDYIQTHYKASRIVLAAAGG 229
              ||    :.::.:.:|..||:...:|.....||:|:..|.:..|..|::.:|...|:|||.. |
Human   196 --NLRPDPEPLLTEMIHEAAYRENTVGLHRFCPTENVAKINREVLHSYLRNYYTPDRMVLAGV-G 257

  Fly   230 VKHDDLVKLACSSLGGLE-----ASVLPAEVTPCRFTG---------SEVRVRDDSLP-LAHVAI 279
            |:|:.||..|...|.|::     |..:..:.:..::||         |.|.:....:| |.|:.:
Human   258 VEHEHLVDCARKYLLGVQPAWGSAEAVDIDRSVAQYTGGIAKLERDMSNVSLGPTPIPELTHIMV 322

  Fly   280 AVEGCGWTDQDNIPLMVANTLVGAWDRSQGGGANNASNLARAS---------AEDNLCHSFQSFN 335
            .:|.|.:.::|.||..|.|.::|      |||:.:|....:..         ...:..::..|::
Human   323 GLESCSFLEEDFIPFAVLNMMMG------GGGSFSAGGPGKGMFSRLYLNVLNRHHWMYNATSYH 381

  Fly   336 TCYKDTGLWGIYFVCDPLQCEDMLFNVQTEWMRLCTMVTEAEVERAKNLLKTNMLLQLDGTTPIC 400
            ..|:||||..|:...||.|..:|:..:..|::.:...|...|:||||..|.:.:::.|:....|.
Human   382 HSYEDTGLLCIHASADPRQVREMVEIITKEFILMGGTVDTVELERAKTQLTSMLMMNLESRPVIF 446

  Fly   401 EDIGRQILC-YNRRIPLHEL 419
            ||:|||:|. .:|::| |||
Human   447 EDVGRQVLATRSRKLP-HEL 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UQCR-C1	NP_650401.1	PqqL	39..453	CDD:440377	126/424 (30%)
PMPCA	XP_005266116.1	PqqL	62..441	CDD:440377	113/387 (29%)