DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment UQCR-C1 and mppb-1

DIOPT Version :9

Sequence 1:	NP_650401.1	Gene:	UQCR-C1 / 41800	FlyBaseID:	FBgn0038271	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_501576.2	Gene:	mppb-1 / 177725	WormBaseID:	WBGene00013880	Length:	458	Species:	Caenorhabditis elegans

Alignment Length:	428	Identity:	224/428 - (52%)
Similarity:	295/428 - (68%)	Gaps:	0/428 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 ATLQKTLLNIPATQVTKLDNGLRVASEDSGASTATVGLWIDAGSRSENEKNNGVAHFLEHMAFKG 93
            |.:|...:.:|.|.||.|.||.|||:|::|.||||:|::||||||.|||||||.|||||||||||
Worm    18 AQVQPKSVFVPETIVTTLPNGFRVATENTGGSTATIGVFIDAGSRYENEKNNGTAHFLEHMAFKG 82

  Fly    94 TAKRSQTDLELEVENLGAHLNAYTSREQTVFYAKCLSKDVPKAVEILADIIQNSKLGEAEIARER 158
            |.:|::..|||||||:|||||||||||.|.:||||.::.:.::|:||:||:.||.|...:|..||
Worm    83 TPRRTRMGLELEVENIGAHLNAYTSRESTTYYAKCFTEKLDQSVDILSDILLNSSLATKDIEAER 147

  Fly   159 SVILREMQEVESNLQEVVFDHLHATAYQGTPLGQTILGPTKNIQSIGKADLTDYIQTHYKASRIV 223
            .||:|||:||..|.||||||.|||..::|.||..|||||.:.||:|.|.||..||.|||::.|:|
Worm   148 GVIIREMEEVAQNFQEVVFDILHADVFKGNPLSYTILGPIELIQTINKNDLQGYINTHYRSGRMV 212

  Fly   224 LAAAGGVKHDDLVKLACSSLGGLEASVLPAEVTPCRFTGSEVRVRDDSLPLAHVAIAVEGCGWTD 288
            |||||||.||.:||:|....|.|:......|..|..::..|||.....||:.:.|:.|||..||.
Worm   213 LAAAGGVNHDAIVKMAEKYFGELKHGDSSTEFVPATYSPCEVRGDIPDLPMLYGAMVVEGVSWTH 277

  Fly   289 QDNIPLMVANTLVGAWDRSQGGGANNASNLARASAEDNLCHSFQSFNTCYKDTGLWGIYFVCDPL 353
            :||:.|||||||:|.:||.:|.|.|..:.||...::|.....|||||||||:|||.|.|||..|.
Worm   278 EDNLALMVANTLMGEYDRMRGFGVNAPTRLAEKLSQDAGIEVFQSFNTCYKETGLVGTYFVAAPE 342

  Fly   354 QCEDMLFNVQTEWMRLCTMVTEAEVERAKNLLKTNMLLQLDGTTPICEDIGRQILCYNRRIPLHE 418
            ..::::.:|..:|:.|...:.||.|:|||..|.||:||.|||:||:|||||||:|||.||||..|
Worm   343 SIDNLIDSVLQQWVWLANNIDEAAVDRAKRSLHTNLLLMLDGSTPVCEDIGRQLLCYGRRIPTPE 407

  Fly   419 LEQRIDAVSVGNVRDVAMKYIYDRCPAVAAVGPVENLP 456
            |..||::::|..:|||..:...:...:.|.||..:..|
Worm   408 LHARIESITVQQLRDVCRRVFLEGQVSAAVVGKTQYWP 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
UQCR-C1	NP_650401.1	PqqL	35..459	CDD:223685	222/422 (53%)
mppb-1	NP_501576.2	PqqL	20..440	CDD:223685	221/419 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158661
Domainoid	1	1.000	198	1.000	Domainoid score	I1805
eggNOG	1	0.900	-	-		E1_COG0612
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3160
Inparanoid	1	1.050	441	1.000	Inparanoid score	I929
Isobase	1	0.950	-	0	Normalized mean entropy	S617
OMA	1	1.010	-	-		QHG53495
OrthoDB	1	1.010	-	-		D287307at33208
OrthoFinder	1	1.000	-	-		FOG0001232
OrthoInspector	1	1.000	-	-		oto18309
orthoMCL	1	0.900	-	-		OOG6_100777
Panther	1	1.100	-	-	LDO	PTHR11851
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R743
SonicParanoid	1	1.000	-	-		X964
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	17	16.790