Protein Alignment Rrp6 and Exosc10

DIOPT Version :10

• Sequence 1: NP_001097795.1
• Gene: Rrp6 / 41798
• FlyBaseID: FBgn0038269
• Length: 900
• Species: Drosophila melanogaster
• Sequence 2: XP_006539086.1
• Gene: Exosc10 / 50912
• MGIID: 1355322
• Length: 898
• Species: Mus musculus
• Alignment Length: 302
• Identity: 55/302 - (18%)
• Similarity: 98/302 - (32%)
• Gaps: 125/302 - (41%)

  Fly    21 REEPYHTLKVPFSSAKGGQISKEVFIEFY----SHTVLTEQDVALRMTVLSSEEVSMSVDKCGKR 81
            |..|.: :.:|||           ||::|    .|:|    :.|||.:.:...:.|      .:.
Mouse   397 RTNPLN-ITLPFS-----------FIDYYKKFRGHSV----EHALRKSNVDFVKWS------SQG 439

  Fly    82 LFETSEDIKNATYLFTREWIDTILTGIYEICTVKNEYQIDITIDCKGPCNGTIIFSISNQQPENI 146
            :...|.|..||.:   :..||:|:                                      |::
Mouse   440 MLRMSPDAMNALF---KPTIDSII--------------------------------------EHL 463

  Fly   147 QDKKSNPAEGSIPF------------------ATSGDSVPVNVSSDIGL-VIEAAF---MNPSVR 189
            :|....|...::.|                  |..||...:.:..|:|| :::.|.   ::|:|
Mouse   464 RDLFQKPEVSTVKFLFLVGGFAEAPLLQQAVQAAFGDKCRIIIPQDVGLTILKGAVLFGLDPAV- 527

  Fly   190 VEIEVEYSTPYTMVIGKCGLTMLRLEGNGE----LKKHNFGW-----------DETKLL-RLVKA 238
              |:|..| |.|..:   |:....:||...    |.|....|           |::..| .|||.
Mouse   528 --IKVRRS-PLTYGV---GVLNRYVEGKHPPEKLLVKDGTRWCTDVFDKFISADQSVALGELVKR 586

  Fly   239 TQCP-------------GDNSDTIDYVMSSEKAGSGTLKFSM 267
            :..|             ...:|.:.::........|||:..:
Mouse   587 SYTPAKPSQLVIIINIYSSENDDVSFITDPGVKKCGTLRLDL 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rrp6	NP_001097795.1	PMC2NT	55..127	CDD:462352	11/71 (15%)
		Rrp6p_like_exo	268..456	CDD:99850	55/302 (18%)
		HRDC	485..565	CDD:128635
		PTZ00121	<619..815	CDD:173412
Exosc10	XP_006539086.1	PMC2NT	44..133	CDD:462352
		Rrp6p_like_exo	285..474	CDD:99850	24/139 (17%)
		HRDC	503..583	CDD:128635	19/86 (22%)