Protein Alignment Rrp6 and exosc10

DIOPT Version :10

• Sequence 1: NP_001097795.1
• Gene: Rrp6 / 41798
• FlyBaseID: FBgn0038269
• Length: 900
• Species: Drosophila melanogaster
• Sequence 2: XP_012821790.1
• Gene: exosc10 / 407941
• XenbaseID: XB-GENE-946594
• Length: 897
• Species: Xenopus tropicalis
• Alignment Length: 966
• Identity: 310/966 - (32%)
• Similarity: 472/966 - (48%)
• Gaps: 198/966 - (20%)

  Fly    20 DQPPKKSASE------DVEAFTNKGFKNAIAATKAANAFPQ-GTARALYLSYPGYARVMEDLTQR 77
            ||...:..||      |.:||........::||||:...|| |.....|.|:||:....|...:.
 Frog    20 DQDLSRDNSEPIPGFSDTDAFVKFALGTVVSATKASTGLPQGGDEYDFYRSFPGFRDFCESQGEH 84

  Fly    78 VVALIGNVLHSKDIKGDIKKRQP----EEQFEMVQECNDVLFERITTNLDIKGGLRRNTQQVVEA 138
            ::..:..|:....::..|:.|..    |::|:::.:.|||:.|::...||...||.||.|.::.|
 Frog    85 LLHCMSQVMQYHGLRSHIRDRSRVTLLEDKFDLLVDANDVILEKVGILLDEASGLNRNQQPILPA 149

  Fly   139 QVDVMSSSTSIEPAVASPQTQGTPKAGSWNRTTGTPQRSMVSA--RLFTAKNIVRPQTQFREPVD 201
                     .::|    |:|    ...||||.|....:...|.  ||..||||:|||.:|:|.:|
 Frog   150 ---------GLQP----PKT----IVSSWNRKTSDLSKKGKSETFRLLHAKNILRPQLKFKEKID 197

  Fly   202 NSAQNPFVPRLKEKPNSLKPLA-----------------LLPEYDDAGNVQ--------SYLHPY 241
            || ..|||.:|..|||:.|||.                 :.|...|..:.|        .:.|||
 Frog   198 NS-NTPFVSKLFVKPNAQKPLPEVLRNRLERQQRQEDLDVPPALADFIHQQRMKISEEDMFCHPY 261

  Fly   242 EFELLKFQPPEEQFQKQ--KPVLPALMAETELMVVDTVEKLKQALEELRQAPQIAIDVEHHSYRT 304
            ::||..|.|.|...:|.  :|||.  :.:.....|..:|.|....|:|.|..:.|:|:||||||:
 Frog   262 QYELDHFVPLESSMEKPDIQPVLS--LQDVPCKFVMKLEDLVALNEKLLQCAEFAVDLEHHSYRS 324

  Fly   305 FMGITCLVQMSTRSKDYIFDTLILRDDMHILNLVLTDPKKLKILHGADLDIEWLQRDLSLYIVNM 369
            |:|:|||:|:|||::|||.|.|.||.:|:|||...|:|..:|:|||||.||||||:|..||||||
 Frog   325 FLGLTCLMQISTRTEDYIIDVLELRSNMYILNESFTNPSIIKVLHGADSDIEWLQKDFGLYIVNM 389

  Fly   370 FDTHRAAKALNMARLSLAYLLKHYLDLDVDKSLQLADWRMRPLPQQLVDYARQDTHFLIYVYGRM 434
            ||||:||:.||:.|.||.:||:.|.:::.||..||||||:||||:::::|||.|||:|:::|.:|
 Frog   390 FDTHQAARILNLGRHSLDHLLRLYCNVESDKRYQLADWRIRPLPEEMIEYARADTHYLLFIYDKM 454

  Fly   435 TNDLL-QQHAEPGLLGSVYQQSTDVCKKRYNKPHIGPESHLDLVRKTKRSFDNRQLYALRGIFEW 498
            ...|| ..:.:..||..|:|:|.|:|.|::.|.....:|:|:|.:|.|:..:.:||.|.|.:|.|
 Frog   455 RTALLGAANKQQNLLQLVWQKSRDICLKKFTKSIFTEDSYLELYQKQKKHLNTQQLTAFRLLFAW 519

  Fly   499 RDATARSEDESYGYVLPNHMMLQIAESLPREMQGILACCNPIPPLVRQQLHTLHQIVLKARDQPL 563
            ||..||.||||.||||||||:|:|.|.||:|.|||:|||:|:|||||||::.|..::.:||:.||
 Frog   520 RDKIARQEDESTGYVLPNHMLLKITEELPKEPQGIIACCSPVPPLVRQQINELSLLIHQARETPL 584

  Fly   564 VKPILEAHSSTQAALPPSTKDFSSKLYCPHDFS-QLEE-----------------------IRDD 604
            :|.  |..|:.:.....:.:...:.|:.|||.| ||.:                       ..|:
 Frog   585 LKS--EISSAKKKGPMANPERMENLLFGPHDTSLQLADNNHLYSGTVLCVFPGLQNSEGSLFTDE 647

  Fly   605 LPT---------LLKRNSTTGKLEVPNKEEVAKVDPTLAAPA--------MALFEKQSKPTQEEE 652
            .|.         :|.|.|.|    :.|..|..:|.|:...|.        :..||...|.....|
 Frog   648 EPVVPVPMNPAFILSRASIT----IFNGFEDEEVVPSKNWPVSQQKARNILESFENPFKMFLPPE 708

  Fly   653 QRWAHLRKESQTMRM-PYKRYLAI-----LPLMVQLKADQLARERSELQKRQLCPAAPTVEQNIK 711
            .|.||:   ||..:: |..:...|     |..:.|.:.:..|:|.:..|||:
 Frog   709 DRRAHV---SQAAKLDPNTKMFEISKQWKLVSLAQQEKEAKAKEDARRQKRE------------- 757

  Fly   712 LEAHAIGKEDDDMYSVPLKEQLKRKHPQANVKTDPEQQPTASKRPRKDENSQTKPPVKIEPVEKV 776
                               |:..|:..:.:.|:..|.|.:..::.:.:|:|:.:
 Frog   758 -------------------EKAAREQAKRDFKSSVENQKSVREQAKDEESSKKR----------- 792

  Fly   777 QQALGESDDEVVEVPIERQATEPPKPSPAQNNRKQKKNQFQRGFKAKNRGNHPQSSSQQVPQHKG 841
                            ||.::||...: .::::|:.||        ......|.|.:...|
 Frog   793 ----------------ERVSSEPGSET-MKSDKKRIKN--------SEETQEPVSQAPFTP---- 828

  Fly   842 TGNFDYKNVDFRQFKGGAQRARGTEI---KQQIRGKNRP-NNRNNKQF--NKLFTF 891
               |||...||:.|.|.:.....:|.   ||..:||.:. :.|...|.  ||..:|
 Frog   829 ---FDYSKSDFKMFAGSSNVKSQSEFDPNKQTHKGKQKNISTRKGHQLMGNKSMSF 881

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rrp6	NP_001097795.1	PMC2NT	55..127	CDD:462352	17/75 (23%)
		Rrp6p_like_exo	268..456	CDD:99850	96/188 (51%)
		HRDC	485..565	CDD:128635	47/79 (59%)
		PTZ00121	<619..815	CDD:173412	36/209 (17%)
exosc10	XP_012821790.1	PMC2NT	49..138	CDD:462352	23/88 (26%)
		Rrp6p_like_exo	287..477	CDD:99850	96/189 (51%)
		HRDC	506..586	CDD:128635	47/79 (59%)
		tolA_full	706..>793	CDD:274303	22/148 (15%)