DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3631 and SAMD7

DIOPT Version :9

Sequence 1:	NP_650398.3	Gene:	CG3631 / 41797	FlyBaseID:	FBgn0038268	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_001291295.1	Gene:	SAMD7 / 344658	HGNCID:	25394	Length:	446	Species:	Homo sapiens

Alignment Length:	218	Identity:	39/218 - (17%)
Similarity:	63/218 - (28%)	Gaps:	97/218 - (44%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 FRNKLLKNYKAAPYENASVLWDIANWWPHENEVYPLYDSSMGQLLETLRREPITRVSNLGRGTQL 132
            |....|:|.:..|...|:.        ||       ::.|.||....||:       |.|
Human   152 FHRSTLRNLQGNPMLAATA--------PH-------FEESWGQRCRRLRK-------NTG----- 189

  Fly   133 KLLVRLSHQQKVIFKPQWYPREEVIDGMIYSGKDRHTAEVYAFYLGAVLDFRWTPIVVGRVVNLK 197
                                .::.:|....|.|.:...::    ||..           ..|..:
Human   190 --------------------NQKALDSDAESSKSQAEEKI----LGQT-----------HAVPYE 219

  Fly   198 KEIYAKGDPELQQTINIETDEDGREKYCLFGKCHYCNEEET-----VCGDERHNIEGVLIYIVPG 257
            ::.||| ||:::...|.::.|              .||:.|     .||:           :.|
Human   220 EDHYAK-DPDIEAPSNQKSSE--------------TNEKPTTALANTCGE-----------LEP- 257

  Fly   258 TLAKRRSPWQRTYKDDKRAPWED 280
               ..|.||.......|...|:|
Human   258 ---THRKPWGSHTTTLKAKAWDD 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3631	NP_650398.3	FAM20_C_like	224..414	CDD:297333	12/62 (19%)
SAMD7	NP_001291295.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	187..207		5/44 (11%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	225..277		16/81 (20%)
		SAM_Samd7,11	324..391	CDD:188978
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3829
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900