DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3631 and Fam20b

DIOPT Version :9

Sequence 1:	NP_650398.3	Gene:	CG3631 / 41797	FlyBaseID:	FBgn0038268	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_001100657.1	Gene:	Fam20b / 304885	RGDID:	1311162	Length:	409	Species:	Rattus norvegicus

Alignment Length:	335	Identity:	138/335 - (41%)
Similarity:	195/335 - (58%)	Gaps:	18/335 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 WDIANWWPHENEVYPLYDSSMGQLLETLRREPITRVSNLGRGTQLKLLVRLSHQQKVIFKPQWYP 152
            |:||..|....||||.....:|.::..:..:.|.:.....:|||||.|:.|...|||:|||:.|.
  Rat    64 WEIAAQWVVPREVYPEETPELGAVMHAMATKKIIKADVGYKGTQLKALLTLEGGQKVVFKPKRYS 128

  Fly   153 REEVIDGMIYSGKDRHTAEVYAFYLGAVLDFRWTPIVVGRVVNLKKEIYAKGDPELQQT-INIET 216
            |:.|::|..|:|.|||.|||.||:|..:|.||..|:||||.|||:.|:......:|..| :.:..
  Rat   129 RDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRYVNLRTEVKPVATEQLLSTFLTVGN 193

  Fly   217 DEDGREKYCLFGKCHYCNEEETVCGDERHNIEGVLIYIVPGT--LAKRRSPWQRTYKDDKRAPWE 279
            :.      |.:|||:||.|.|..|.| ...:||.:...:|..  |.|.|.||.|||::.|.|.||
  Rat   194 NT------CFYGKCYYCRETEPACAD-GDMMEGSITLWLPDVWPLQKHRHPWGRTYREGKLARWE 251

  Fly   280 DDMTYCKSLKNKM---ETIRLLDLIDASIFDYLIQNGDRHHYETREE-----RVVLIDNGKAFGN 336
            .|.:||.::|...   ...||||:||.::|||||.|.||||||:.::     .::|:||.|:|||
  Rat   252 YDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGN 316

  Fly   337 PNKDHLDILAPLYQCCLLRKSTWDRLQVFSGGVLTEIIDRLSKQDALYPLITDKHKKGVERRLLV 401
            |:.|...|||||||||::|.|||:||.....|||...:......|.:.|:::|.|...|::|||.
  Rat   317 PSLDERSILAPLYQCCIIRVSTWNRLNYLKNGVLKSALKSAMAHDPIAPVLSDPHLDTVDQRLLN 381

  Fly   402 VYAVVEHCMD 411
            |.|.::.|.|
  Rat   382 VLATIKQCTD 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3631	NP_650398.3	FAM20_C_like	224..414	CDD:297333	86/198 (43%)
Fam20b	NP_001100657.1	FAM20B_C	188..394	CDD:198461	86/211 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341800
Domainoid	1	1.000	101	1.000	Domainoid score	I6813
eggNOG	1	0.900	-	-		E1_KOG3829
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8909
Inparanoid	1	1.050	260	1.000	Inparanoid score	I3040
OMA	1	1.010	-	-		QHG49094
OrthoDB	1	1.010	-	-		D227822at33208
OrthoFinder	1	1.000	-	-		FOG0008106
OrthoInspector	1	1.000	-	-		oto98059
orthoMCL	1	0.900	-	-		OOG6_109176
Panther	1	1.100	-	-	LDO	PTHR12450
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6056
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810