Protein Alignment CG14857 and SLC22A13

DIOPT Version :10

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_004247.2
• Gene: SLC22A13 / 9390
• HGNCID: 8494
• Length: 551
• Species: Homo sapiens
• Alignment Length: 550
• Identity: 153/550 - (27%)
• Similarity: 249/550 - (45%)
• Gaps: 76/550 - (13%)

  Fly     3 FDQILEKCGSAGRYQYLMILLLGYIAFTTTVHYYSQNIIGFVPQHWCYHEALENRSFEEIAA--- 64
            |.|:|.:.|..||:|..:::||..:.|.:..::::...:.....|.|....::|.:|...||
Human     4 FVQVLAEIGDFGRFQIQLLILLCVLNFLSPFYFFAHVFMVLDEPHHCAVAWVKNHTFNLSAAEQL 68

  Fly    65 ----------------IYAPFGKEASCTRLDKIEGDRVTVSNET--CQR-WIYNYDFGFRSMNAE 110
                            ::.|....||   |..|...|.   |||  |.. |.|. :....|:..|
Human    69 VLSVPLDTAGHPEPCLMFRPPPANAS---LQDILSHRF---NETQPCDMGWEYP-ENRLPSLKNE 126

  Fly   111 LNWVCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAVILA-----NQCGFVGDFLTTYAS 170
            .|.||:..:.....||:|..|.|:||..||.|.||||| :|.|||     ...|....|:.::..
Human   127 FNLVCDRKHLKDTTQSVFMAGLLVGTLMFGPLCDRIGR-KATILAQLLLFTLIGLATAFVPSFEL 190

  Fly   171 NL-VQFAIFRCISGLAATANYYLMFILVLEYLAPKLRNMAISGTLGIC-FCLGALVAPWLSVLAG 233
            .: ::||:...::||:     :....|:.|::.|..|..|:  .|..| |.||.:|...|:....
Human   191 YMALRFAVATAVAGLS-----FSNVTLLTEWVGPSWRTQAV--VLAQCNFSLGQMVLAGLAYGFR 248

  Fly   234 NWRIYLTCSALLQLVVALFYFVVQESAQWLITRTNVEGAIARLKHIAHFNGMEVKAADFEAFRRN 298
            |||:.........|::..:::.:.|||:||:||..::.||..::..|..|
Human   249 NWRLLQITGTAPGLLLFFYFWALPESARWLLTRGRMDEAIQLIQKAASVN--------------- 298

  Fly   299 CIVKRKLS----NQ--PEQT---AGIFDLLRTPNLRKVSLLVVFTFMLTSLSFNTISRNVEGMGL 354
               :||||    ||  ||:|   ....||.|.|.||||:|::...:.:.||.:..:|..|...||
Human   299 ---RRKLSPELMNQLVPEKTGPSGNALDLFRHPQLRKVTLIIFCVWFVDSLGYYGLSLQVGDFGL 360

  Fly   355 SPFVVFSLFAVVVPPSGFIQGLLQSRVGRKATAFLAMLCTGLLSCALGVALSTEGAQKNVTLLLA 419
            ..::...:|..|..|:......:..|.|||.:. |..|..|.|.|.:.:.:..: ....||:|
Human   361 DVYLTQLIFGAVEVPARCSSIFMMQRFGRKWSQ-LGTLVLGGLMCIIIIFIPAD-LPVVVTML-- 421

  Fly   420 FALPMRLGISMCYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIHLGTKLAAAPSLIL 484
             |:..::..:..:|::..:::||.||.:|..|:..|.:.:.....::|.:|.||...||.|.||.
Human   422 -AVVGKMATAAAFTISYVYSAELFPTILRQTGMGLVGIFSRIGGILTPLVILLGEYHAALPMLIY 485

  Fly   485 ALLLLTASGCTLMLPETNNRQLPITLADGE 514
            ..|.:.|.....:||||:.:.|..||.|.|
Human   486 GSLPIVAGLLCTLLPETHGQGLKDTLQDLE 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	146/535 (27%)
SLC22A13	NP_004247.2	MFS_OAT	102..500	CDD:340932	123/432 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	511..551		2/4 (50%)