Protein Alignment CG14857 and TPO1

DIOPT Version :10

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_013072.1
• Gene: TPO1 / 850631
• SGDID: S000003951
• Length: 586
• Species: Saccharomyces cerevisiae
• Alignment Length: 522
• Identity: 98/522 - (18%)
• Similarity: 158/522 - (30%)
• Gaps: 191/522 - (36%)

  Fly    77 RLDKI------EGDRVTVSNETC--------------QRWIYNYDF-GFRSMNAELNW------- 113
            ||.||      |.|||.|....|              .|.:|...| |........||
Yeast    83 RLTKILTGSVNEPDRVEVDYTNCAPMGGDRPYPPSLPSRDLYEVTFDGPNDPLHPFNWPMKKKVL 147

  Fly   114 -------------VCNDAYK----------------ARIGQSLFFLGSLMGTFTFGVLGDRIGRV 149
                         :|:..:.                |.:|.:||.||.......:..|.:..||
Yeast   148 LCLVLCLDSIAIAMCSSIFASAVPQICEIYHVIEVVAILGITLFVLGFAASPVIYAPLSELYGR- 211

  Fly   150 RAVILANQCGF-VGDFLTTYASNLVQFAIFRCISGLAATANYYLMFILVLEYLAPKLRNMAISGT 213
            :.|::.:..|| :..|....|.||....|.|...|....|...::.....:.....:|..||:
Yeast   212 KGVLVLSAFGFALFQFAVATAENLQTIFICRFFGGFIGAAPMAVVPAAFADMFDTNVRGKAIA-- 274

  Fly   214 LGICFCLGALVAPWLSVLAGN---------WRIYLT-CSALLQLVVALFYF-------VVQESAQ 261
               .|.||..|.|.||.:.|:         |..|:. |.|....|..:.:|       ::...|:
Yeast   275 ---LFSLGVFVGPILSPVMGSYIAQRTTWRWLEYVVGCFASAVFVAIVLFFEETHHPTILVNKAK 336

  Fly   262 WLITRTNVEGAIARLKHIAHFNGMEVKAADFEAFRRNCIVKRKLSNQPEQTAGIFDLLRTPNLRK 326
            .:..::|..|.     |.|| ..:|:...|        ||::
Yeast   337 QMRKQSNNWGI-----HAAH-EDVELSIKD--------IVQK----------------------- 364

  Fly   327 VSLLVVFTFMLTSLSFNTISRNVEGMGLSPFVVFSLFAVVVPPSGFIQGLLQSRVGRKATAFLAM 391
                             |::|.:..:.:.|.::|     |...:.|:.|:|...:......|:.
Yeast   365 -----------------TVTRPIIMLFVEPLLLF-----VTIYNSFVYGILYLLLEAYPLVFVE- 406

  Fly   392 LCTGLLSCALGVALSTEGAQKNVTLLLAFALPMRLGISMCYTVTSQFASELLPTCVRSRG--IAA 454
                      |...:..|....:.|:        :|:.:|........::.|..| |::|  :..
Yeast   407 ----------GYGFTENGELPYIALI--------IGMMVCAAFIWYMDNDYLKRC-RAKGKLVPE 452

  Fly   455 VHLAA---AGASF-----------VSPYLIH---------------LGTKLAAAPSLILALLLLT 490
            ..|.|   ||..|           ..|:.||               :|..|.....:|.:.|||.
Yeast   453 ARLYAMVIAGTVFPIGILWFCWTGYYPHKIHWMVPTVGGAFIGFGLMGIFLPCLNYIIESYLLLA 517

  Fly   491 AS 492
            ||
Yeast   518 AS 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	98/522 (19%)
TPO1	NP_013072.1	MFS_Tpo1_MDR_like	156..577	CDD:340881	82/449 (18%)