DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14857 and OCT5

DIOPT Version :9

Sequence 1:	NP_650392.1	Gene:	CG14857 / 41791	FlyBaseID:	FBgn0038262	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	NP_178059.1	Gene:	OCT5 / 844279	AraportID:	AT1G79410	Length:	515	Species:	Arabidopsis thaliana

Alignment Length:	556	Identity:	129/556 - (23%)
Similarity:	231/556 - (41%)	Gaps:	117/556 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFDQILEK-CGSAGRYQYLMILLLGYIAFTTTVHYYSQNIIGFV-----PQHWCYHEALENRSF 59
            :.||:|||| ....|..|:|.|:|:| :|.|    :.||.|...|     |...|....:.|.:.
plant    23 LTFDKILEKSLSDFGFSQFLQIVLVG-LALT----FDSQQIFITVFTDAYPTWHCLDHTICNPAT 82

  Fly    60 EEIAAIYAPFGKEASCTRLDKIEGDRVTVSNETCQRWIYNYDFGF--RSMNAELNWVCNDAYKAR 122
            .:|..|                            .|..:::|.||  :|:.:|.:..|:.::...
plant    83 TDICKI----------------------------PRSAWDWDGGFKGKSVISEFDLECSSSFLRS 119

  Fly   123 IGQSLFFLGSLMGTFTFGVLGD-RIGRVRAVILANQCGFVGDFLTTYASNLVQFAIF-------- 178
            :..|.|::||::|.....::.| .:||.:.:           |.:::|.:|...:||
plant   120 LPSSTFYVGSIVGGVVLAMIPDGSLGRKQLL-----------FFSSFAMSLTGISIFLSSNIWIY 173

  Fly   179 ---RCISGLAATANYYLMFILVLEYLAPKLRNMA--ISGTLGICFCLGALVAPWLSVLA--GNWR 236
               :.:.|.|.:.......:|:.|.::.|.|..|  :..||   |.||.:....::.|.  .:|:
plant   174 SFLKFVIGFARSQTGTYALVLISERISTKWRPRATMVPFTL---FVLGFMSLSGIAYLVRHASWK 235

  Fly   237 IYLTCSALLQLVVALF-YFVVQESAQWLITRTNVEGAIARLKHIAHFNGMEVKAADFEAFRRNCI 300
            :...|:::...:.::| ||...||.:||......:.||..||.|:..|         ..:..:..
plant   236 VLYLCTSIPAGIHSIFIYFFALESPRWLHLEGKNKEAIEVLKRISPAN---------RGYLESVS 291

  Fly   301 VKRKLSNQPEQTA--GIFDLLRTP-NLRKVSLLVVFTFMLTSLSFNTISRNVEGMGLSPFVVFSL 362
            .:.:.....|||:  .|.||.... ..|:|:|:::..|.| .:|:..:...|..:.::.::..:|
plant   292 SRLRPKETLEQTSSYSIKDLFIIKWAFRRVTLVMIIMFGL-GMSYYGVPLAVRDIKVNIYMSEAL 355

  Fly   363 FAVVVPPSGFIQGLLQSRVGRKATAFLAMLCTGLLSCALGVA-------LSTEGAQKNVTLLLAF 420
            .|:|..|:..:..:|..:..|:::.        |::|.:|.|       :|..|..|     :||
plant   356 NAMVELPTFVVTPILLEQFSRRSSV--------LVNCLIGGASGVLCFVMSLYGRTK-----IAF 407

  Fly   421 ALPMRLGISMC----YTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIHLGTKLAAAPS 481
            ||  .||...|    :.:.:.:..||.|||||:.....:..|........|.:..||..:   ||
plant   408 AL--ELGSFFCARIGFNLMAIYLVELFPTCVRNSATMMLRQALVVGGACCPLIASLGRNV---PS 467

  Fly   482 LILALLLLTASGC---TLMLPETNNRQLPITLADGE 514
            |..|:.....||.   .|:||||....|..|:.:.|
plant   468 LSFAVFGFAMSGLGLFALLLPETKGLSLCDTMEEQE 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	121/538 (22%)
CG14857	NP_650392.1	MFS	126..470	CDD:119392	83/374 (22%)
OCT5	NP_178059.1	MFS_OCT_plant	83..488	CDD:340936	101/474 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010