DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14857 and OCT2

DIOPT Version :9

Sequence 1:	NP_650392.1	Gene:	CG14857 / 41791	FlyBaseID:	FBgn0038262	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	NP_178054.1	Gene:	OCT2 / 844274	AraportID:	AT1G79360	Length:	527	Species:	Arabidopsis thaliana

Alignment Length:	559	Identity:	128/559 - (22%)
Similarity:	209/559 - (37%)	Gaps:	116/559 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 DQILEKCGSAGRYQYLMILLLGY-----------IAFT---TTVHYYSQNIIGFVPQHWCYHEAL 54
            |.|....||.|..|:|...|:.:           ..||   .|.|....|.|       | ||::
plant    22 DTIESYIGSFGWAQFLQAALVSFSGVFDAQQTFISVFTDSEPTWHCTDSNSI-------C-HESI 78

  Fly    55 ENRSFEEIAAIYAPFGKEASCTRLDKIEGDRVTVSNETCQRWIYNYDFGFRSMNAELNWVCNDAY 119
            .|                             :.:..:|...|.|:...   |:.:|....|..::
plant    79 SN-----------------------------ICILPKTAWSWDYSPHV---SVISEWGLQCAGSF 111

  Fly   120 KARIGQSLFFLGSLMGTFTFGVLGD-RIGRVRAVILANQCGFVGDFLTTYASNLVQFAIFRCISG 183
            ...:.:|.||:|.|:|......|.| .:||...:.|:.....:...||.::.|:..:|:.|.::|
plant   112 VKGLPESSFFVGCLIGGLVLSTLADSSLGRKNMLFLSCLVMAISTMLTVFSPNIWVYAVLRFVNG 176

  Fly   184 LAATANYYLMFILVLEYLAPKLRNMAISGTLGIC----FCLGALVAPWLSVL--AGNWRIYLTCS 242
            ...........:|..|.:..|.|     |.:||.    |.||.|..|.::.:  ..:|||....:
plant   177 FGRATIGTCALVLSTELVGKKWR-----GRVGIMSFFGFMLGFLSLPLMAYMNRGSSWRILYAWT 236

  Fly   243 ALLQLV-VALFYFVVQESAQWLITRTNVEGAIARLKHIAHFNGMEVKAADFEAFRRNCIVKRKLS 306
            ::..:: ..|..|.|.||.:||..|...|.||:.||.:|.....:|.:....:...:.:...:..
plant   237 SIPTIIYCVLVRFFVCESPRWLFVRGRREEAISILKRVASIPSTDVSSGGAISMSFSSLPFEEDE 301

  Fly   307 NQPEQTAGIFDLLRTP-----NLRKVSLLVVFTF-----------MLTSLSFNTISRNVEGMGLS 355
            .:|.....||..::..     .|:::|.::...|           .|::|.||.
plant   302 EKPSTNVNIFTTMKVLVEKRWALKRLSAVMAIAFGIGLVYYGMPLALSNLDFNI----------- 355

  Fly   356 PFVVFSLFAVVVPPSGFIQGLLQSRVGRKATAFLAMLCTGLLSCALGVAL-----STEGA-QKNV 414
             ::..:..|::..|:..|...|..::.|: .|.:.....|.:|..|..||     ...|| |..:
plant   356 -YLSAAFNALMDLPANLITLFLVDKLSRR-NALIGFTALGGVSSVLIFALHNMRIGNHGALQLAL 418

  Fly   415 TLLLAFALPMRLGISMCYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIHLGTKLA-- 477
            .|:..|:......:.|.||:      ||.|||||:..||....|.......||.::..|.|.|
plant   419 ELISYFSACSAFNMEMIYTI------ELFPTCVRNSAIAMARQALVLGGVFSPIMVAAGRKNAFW 477

  Fly   478 --AAPSLILALLLLTASGCTLMLPETNNRQLPITLADGE 514
              ....|.:.||.|.|.|    ||||....|..|:.:.|
plant   478 SFGLFGLAIGLLGLFAVG----LPETRGSDLCDTMDEEE 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	124/545 (23%)
CG14857	NP_650392.1	MFS	126..470	CDD:119392	88/373 (24%)
OCT2	NP_178054.1	MFS_OCT_plant	79..497	CDD:340936	104/477 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.020