DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14857 and OCT4

DIOPT Version :9

Sequence 1:	NP_650392.1	Gene:	CG14857 / 41791	FlyBaseID:	FBgn0038262	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	NP_188702.2	Gene:	OCT4 / 821613	AraportID:	AT3G20660	Length:	526	Species:	Arabidopsis thaliana

Alignment Length:	537	Identity:	129/537 - (24%)
Similarity:	225/537 - (41%)	Gaps:	77/537 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 DQILEK-CGSAGRYQYLMILLLGYIAFTTTVHYYSQNIIGFVPQHWCYHEALENRSFEEIAAIYA 67
            |::|:: ||..||:|      |.:...|                  |...|||  :|..:..|:|
plant    35 DEMLQRYCGEFGRWQ------LKHFVLT------------------CIAWALE--AFHTMVMIFA 73

  Fly    68 PFGKEASCTRLDKIEGDRVTVSNETCQ----RWIYNYDFGFRSMNAELNWVCNDAYKARIGQSLF 128
            ....|..|.      |....|.:..|:    .|.:....| .|..:|...:|.|.||..:.|:||
plant    74 DQEPEWRCV------GSDCRVGSLNCELDPSSWEWTAGKG-SSTVSEWGLICGDKYKVGLVQALF 131

  Fly   129 FLGSLMGTFTFGVLGD-RIGRVRAVILANQCGFVGDFLTTYASNLVQFAIFRCISGLAATANYYL 192
            |.|.::|...||.|.| ::||..::.:......:....|.::.|...:.:.|.::|.:.......
plant   132 FAGCMIGAGVFGHLSDSKLGRKGSLTVVCIINAIFGIATAFSPNYWTYVVLRFLTGFSTGGVGLT 196

  Fly   193 MFILVLEYLAPKLRNMAISGTLGICFCLGALVAPWLSVLAGNWRIYLTCSALLQLVVALFYF-VV 256
            .|:|..|.:.|..|.:|...|. ..|..|..|...::.:..:||.....|:|..|:..|... .:
plant   197 AFVLATEPIGPSKRGVAGMSTF-YFFSAGIAVLSGIAYVFRSWRELFIVSSLPSLLFLLIVIPFI 260

  Fly   257 QESAQWLITRTNVEGAIARLKHIAHFNGMEVKAADFEAF---------RRNCIVKRKLSNQPEQT 312
            .||.:|.:.|..|:.|:..:..||..||..:.|....|.         .||..|:..|.
plant   261 SESPRWYLVRGKVDEAMKLMHSIAKTNGRHIPAGVTLALDDDVENNNGERNTAVEGSLK------ 319

  Fly   313 AGIFDLLRTPNLRK---VSLLVVFTFMLTSLSFNTISRNVEGMGLSPFVVFSLFAVVVPPSGFIQ 374
                |::.:|.:|.   :|:.:.||   .|:.:..:|.||..:..:.::...:.||...|:..|.
plant   320 ----DVILSPLMRMRLVISVAISFT---VSIVYYGLSLNVGNLKTNLYLNVFVNAVSEMPAFAIT 377

  Fly   375 GLLQSRVGRKATAFLAMLCTGLLSCALGVALSTEGAQKNVTLLLAFALPMRLGISMCYTVTSQFA 439
            .:|..:.|||..: :.......:.|.:|.::...|..|:|. :::..|.: .|::..|.:...:.
plant   378 AVLLDKYGRKPLS-IGTQWFSCVFCLVGFSVWGAGPWKSVR-MVSGVLGI-FGMAGTYNLLFIYI 439

  Fly   440 SELLPTCVRSRGIAAVHLAAAGASFVSPYLIHLGTKLAAAPSLILALLLLTASGCTLMLPETNNR 504
            :||.||.||:..:.....||...:.::|:::.||.:|   |..:.|:..|...|....||||.|:
plant   440 AELFPTVVRNAALGCATQAAQMGAILAPFVVVLGEEL---PFGVFAVCGLVGGGLAFYLPETLNK 501

  Fly   505 QLPITLADGEAFGKGES 521
            .|..|:     ||..|:
plant   502 PLYDTM-----FGMHEA 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	122/515 (24%)
CG14857	NP_650392.1	MFS	126..470	CDD:119392	82/357 (23%)
OCT4	NP_188702.2	MFS_OCT_plant	90..496	CDD:340936	99/426 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010