Protein Alignment CG14857 and slc22a7a

DIOPT Version :10

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_001077330.1
• Gene: slc22a7a / 794188
• ZFINID: ZDB-GENE-050506-52
• Length: 560
• Species: Danio rerio
• Alignment Length: 598
• Identity: 159/598 - (26%)
• Similarity: 260/598 - (43%)
• Gaps: 98/598 - (16%)

  Fly     1 MDFDQILEKCGSAGRYQYLMILLLGYIAFTTTVHYYSQNIIGFVPQHWCYHEALENR------SF 59
            |.|:.:|.:.|...::|:|::.:|........:|:...|.|..||.|.|....|:.|      ..
Zfish     1 MRFEDVLREIGGFNKFQFLVLYILWLPRVILPLHFLLHNFISGVPPHHCALPRLDGRFSASGAEK 65

  Fly    60 EEIAAIYA------PFGKEASCTR------------LDKIEGDRVTVSNETCQR-WIYNYDFGFR 105
            ||:|.|.|      ..|..:||..            |..:.|:|..|| ..||. |:|:.. .|.
Zfish    66 EELAQIVALGIPRNSDGSYSSCKMYTMPMDFDLNGDLSVLYGNRSNVS-VPCQNGWVYDRS-QFT 128

  Fly   106 SMNA-ELNWVCNDAYKARIGQSL---FFLGSLMGTFTFGVLGDRIGRVRAVILANQCGFVGDFLT 166
            |..| |.:.||::   .::.|:|   ||:|..||...||.|.|:.||...:.::.....|...:.
Zfish   129 STTATEWDLVCDN---KKLNQALATFFFIGVTMGAVVFGQLSDKFGRKPMIQVSFVSSAVFGIIE 190

  Fly   167 TYASNLVQFAIFRCISGLAATANYYLMFILVLEYLAPKLRNMAISGT-LGICFCLGALVAPWLSV 230
            .::|:.|.|||.|.:.|.|.|........|.:|:...|.|  ..:|| :.:.:.:|.::...|:.
Zfish   191 AFSSSYVMFAIARTLCGFALTGMSITTVALCVEWTDVKHR--TFTGTIISLGWSVGNMLLALLAY 253

  Fly   231 LAGNWR--IYLTCSALLQLVVALFYFVVQESAQWLITRTNVEGAIARLKHIAHFNG--MEVKAAD 291
            |..:||  |.:..|..|..::|.::  :.|||:||:....||.|...|.:.|..||  ...|..|
Zfish   254 LIRDWRHLILVVTSPCLVGIIAWWW--IPESARWLLANGRVEEAQKYLINCAKMNGKYSYTKKLD 316

  Fly   292 FEAFRRNCIVKRKLSNQPEQTAGIFDLLRTPNLRKVSLLVVFTFMLTSLSFNTISRNVEGMGLSP 356
            .|..::..|.:....|.     ...||:|||.|||:.|.....:...:.::..||.|:.|.||:.
Zfish   317 IENLKKITIAEDSNKNH-----SYLDLVRTPKLRKIVLCSGIFWFAVAFTYYGISFNITGFGLNI 376

  Fly   357 FVVFSLFAVVVPPSGFIQGLLQSRVGRKATAFLAMLCTGLLSCALGVALSTEGAQKNVTLLLAFA 421
            ::...::.|:..|:.....|...|:||:.....:::..|.| ..|...:.||.|
Zfish   377 YLTQFIYGVIEVPAKVGTYLTLDRIGRRNGQAWSLIIAGAL-IGLNSVIPTEFA----------- 429

  Fly   422 LPMRLGISM--------CYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLI------HL 472
             .:|.||::        .:|:...:.|||.||.:|..|:......|.....::|.:|      |.
Zfish   430 -AVRTGIAVIGKGFSEAAFTIAFLYTSELYPTVLRQCGLGYTSFIARIGGSLAPMVILFEDIWHY 493

  Fly   473 GTKLAAAPSLILALLLLTASGCTL-MLPETNNRQLPITLADGEAFGKGESMLSFDCWRRHDDDVS 536
            |..:..:.:.:.       |||.: :||||.|.|||..:.|.|   :|          ||  .:|
Zfish   494 GPPVVFSATAVF-------SGCVVFLLPETTNVQLPENILDVE---EG----------RH--TLS 536

  Fly   537 KEATEEVRLHQLN 549
            .||..:|.|:::|
Zfish   537 TEAERDVELNEMN 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	145/546 (27%)
slc22a7a	NP_001077330.1	MFS_SLC22A7_OAT2	109..514	CDD:341005	114/438 (26%)