Protein Alignment CG14857 and Slc22a16

DIOPT Version :10

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_081848.1
• Gene: Slc22a16 / 70840
• MGIID: 1918090
• Length: 649
• Species: Mus musculus
• Alignment Length: 617
• Identity: 137/617 - (22%)
• Similarity: 256/617 - (41%)
• Gaps: 103/617 - (16%)

  Fly     3 FDQILEKCGSAGRYQYLMILLLGYIAFTTTVHYYSQNIIGFVPQHWC----------YHEALENR 57
            ||.|    |..||:|.::.|:..|.:.:..:||.|...:..:|:|.|          :|.....|
Mouse    10 FDHI----GHFGRFQIVLYLICAYQSLSCGIHYLSSVFLSIIPEHACKPPGMVRKAVFHNVSAWR 70

  Fly    58 SFEEIAAIYAPFGKEASCTRLDKIEGDRVTVSNETCQR-WIYN-----YDF-GFR---------- 105
             .|:|.|:.:|..|:.....|...|...:|    .|.| |..|     |:: |::
Mouse    71 -LEDILALRSPEHKDHIMVELQDGEIWELT----RCSRTWRENTSHLGYEYSGYKHDSPCFDGYV 130

  Fly   106 --------SMNAELNWVCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAVILANQCGFVG 162
                    |.....|.||:..:.||:.|.|...|.::|:.||..|.||.||..|:    .|..:|
Mouse   131 YDQSKWRNSAVRNFNLVCDQKWYARMIQPLIIFGVMLGSITFSYLSDRFGRRMAL----WCTSIG 191

  Fly   163 DFLTTYAS----NLVQFAIFRCISGLAATANYYLMFILVLEYLAPKLRNMAISGTLGICFCLGAL 223
            .|....||    :.:.|.|.|....:|::..:.::|:.|:|.:..|.|..| |..|...|.:||:
Mouse   192 VFFFGIASLFIFDYLSFMITRFFLVMASSGYFVVVFVYVMEIIGKKARTWA-SIHLNTFFAIGAM 255

  Fly   224 VAPWLSVLAGNWRIYLTCSALLQLVVALFYFVVQESAQWLITRTNVEGAIARLKHIAHFNG---- 284
            :....|.|...|.:|.....::.....|..:::.|:..||::....:.|...:..:|.:|.
Mouse   256 LVALASYLLKTWWLYQIILCIVTTPFILCCWMLPETPFWLLSEGRYKEAQGTVDTMAVWNKSSSC 320

  Fly   285 --MEVKAADFEAFRRNCIVKRKLSNQPE--QTAGIFDLLRTPNLRKVSLLVVFTFMLTSLSFNTI 345
              :|:.:.|         |.|..:..|.  :...:.||....::.|::|:|...:...:|.:...
Mouse   321 DLVELLSLD---------VTRSHNKSPHSIRKHRLADLFHNLDVAKMTLIVWLDWFTANLGYYMF 376

  Fly   346 SRNVEGMGLSPFVVFSLFAVVVPPSGFIQGLLQSRVGRKATAFLAMLCTGLLSCALGVALSTE-- 408
            .:.|.....:..:...|...:..|:.....:...||||:.|..|.:|.:. |:|.|.|.:.::
Mouse   377 GKEVIRRKENEPLYLLLVGAMEIPAYICLCIWLKRVGRRKTMLLFLLVSS-LTCMLHVVMPSDYK 440

  Fly   409 GAQKNVTLLLAFALPMRLGISMCYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIHLG 473
            .|::.|.||      ::..||..:.....:.:||.||.||...:.:.::.:..:|...|:..|..
Mouse   441 TAKRMVALL------VKSVISSVFAFIYLYTAELYPTTVRCLAVGSSNMVSHVSSIFIPFTSHFS 499

  Fly   474 TKLAAAPSLILALLLLTASGCTLMLPETNN-----------RQLPITLADGEAFGKGESMLSFDC 527
            ......|.::..:|.:.:...:|.||||.:           :|:|   .:.::.|:|... ||:.
Mouse   500 KVWIFLPQILFGILAILSGLLSLKLPETQDTPMKSTWETTEQQVP---ENKDSLGEGPPD-SFER 560

  Fly   528 WRRHDDDVSKEATEEVRLHQLNGQTKSETEAE 559
            |         :::..:...:..|.:::..:||
Mouse   561 W---------DSSRALSFAERWGLSRASPDAE 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	126/557 (23%)
Slc22a16	NP_081848.1	MFS_SLC22A16_CT2	118..525	CDD:340933	93/427 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	530..560		6/33 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	579..649		2/5 (40%)