Protein Alignment CG14857 and sv2a

DIOPT Version :10

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: XP_696434.2
• Gene: sv2a / 568033
• ZFINID: ZDB-GENE-131001-1
• Length: 733
• Species: Danio rerio
• Alignment Length: 675
• Identity: 128/675 - (18%)
• Similarity: 208/675 - (30%)
• Gaps: 257/675 - (38%)

  Fly     3 FDQILEKCGSAGRYQYLMILLLGYIAFTTTVHYYSQNIIGFVPQHWCYHEALENRSFEEIAAIYA 67
            ::.||::||. ||:|:.:..:||.......|..:   ::|||                      .
Zfish   144 YETILQECGH-GRFQWTLYFVLGLALMADGVEIF---VVGFV----------------------L 182

  Fly    68 PFGKEASCTRLDKIEGDRVTVSNETCQRWIYNYDFGFRSMNAELNWVCNDAYKARIGQSLFFLGS 132
            |                                       :||.:...::..|..:| .:.:||.
Zfish   183 P---------------------------------------SAEKDMCLSEPNKGMLG-LIVYLGM 207

  Fly   133 LMGTFTFGVLGDRIGRVRAVILANQCGFVGDFLTTYASNLVQFAIFRCISGLAATANYYLMFILV 197
            ::|.|.:|.|.|||||.:.::::.....|..|.:::......|...|.:||:....:..::|...
Zfish   208 MVGAFVWGGLADRIGRRQTLLISLSINSVFAFFSSFVQGYSSFLFCRLLSGVGIGGSIPIVFSYY 272

  Fly   198 LEYLAPKLRNMAISGTLGICFCLGALVAP-----------WLSVLAG-----NWRIYLTCSALLQ 246
            .|:||.:.|...:| .|.:.:.:|.:.|.           |...:..     :||:::...|...
Zfish   273 SEFLAQEKRGEHLS-WLCMFWMIGGIYAAAMAWAIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPS 336

  Fly   247 LVVALFYFVVQESAQWLITRTNVEGAIARLKHIAHFNGMEVKAADFEAFRRNCI--VKR------ 303
            :........:.||.::.:.....:.|...||.: |...|..|......|....|  ||:
Zfish   337 VAAIAALTTMPESPRFYLENGKHDEAWMILKQV-HDTNMRAKGYPERVFSVTTIKTVKQMDELVD 400

  Fly   304 --------------KLSNQPEQTAGIFDLLRTPNLRKVSLL------------------------ 330
                          ||:|...|..|.|..:..|..|:::.:
Zfish   401 MGGEATAWHQRWRIKLTNLFHQVWGNFLTVFNPEYRRITYMMMAVWFSMSFSYYGLTVWFPDMIK 465

  Fly   331 ---------------------VVFTFML------------------------------------- 337
                                 |.|.|.|
Zfish   466 YLQKQEYSSRTKVFIKEKVEHVTFNFTLENQIHRNGEYFNNKFLNLKMKSMVFEDSLFEECYFED 530

  Fly   338 --------------TSLSFN----------------TISRNVEGMGLS----------PFVVFSL 362
                          ::|.:|                |...|.||..|.          .||.| |
Zfish   531 ITSSNTFFRNCTFISTLFYNTDLFKYRLINSKLINSTFLHNKEGCMLDFSDENNAYMIYFVSF-L 594

  Fly   363 FAVVVPPSGFIQGLLQSRVGRKATAFLAMLC-TGLLSCALGVALS---TEGAQKNVTLLLAFALP 423
            ..:.|.|...:..||..::||     |.||. :.::||.....||   :|.|.  :.||..|.
Zfish   595 GTLAVLPGNIVSALLMDKIGR-----LRMLAGSSVISCVSCFFLSFGNSESAM--IALLCLFG-- 650

  Fly   424 MRLGISMC-YTVTSQFASELLPTCVRSRGI----AAVHLAAA-GASFVSPYLIHLG-TKLAAAPS 481
               |||:. :........||.|:..|:...    |...|||. |.|....:   :| ||  |.|.
Zfish   651 ---GISIASWNALDVLTVELYPSDKRTTAFGFLNALCKLAAVLGISIFQSF---VGITK--AVPI 707

  Fly   482 LILALLLLTASGCTLMLPETNNRQL 506
            |..:..|...|...|.||||..:.|
Zfish   708 LFASGALAAGSFLALKLPETRGQVL 732

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	125/667 (19%)
sv2a	XP_696434.2	synapt_SV2	1..733	CDD:130366	128/675 (19%)