Protein Alignment CG14857 and Slc22a21

DIOPT Version :10

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_062697.1
• Gene: Slc22a21 / 56517
• MGIID: 1929481
• Length: 564
• Species: Mus musculus
• Alignment Length: 559
• Identity: 142/559 - (25%)
• Similarity: 245/559 - (43%)
• Gaps: 85/559 - (15%)

  Fly     1 MDFDQILEKCGSAGRYQYLMILLLGYIAFTTTVHYYSQNII--GF----------VPQH------ 47
            :|:|::....|..|.:|.|:..||            |.:||  ||          :|:|
Mouse     2 LDYDEVTAFLGEWGTFQRLIFFLL------------SASIIPNGFTGLSAVFLTAIPEHRCRIPD 54

  Fly    48 -------WCYHE-ALENRSFEEI--------AAIYAPF-------GKEASCTRLDKIEGDRVTVS 89
                   |..|. .:|.:...|:        .|..|.|       |::....:|::
Mouse    55 TVNLSSAWRNHSIPMETKDGPEVPQKCRRYRLATIANFSELGLEPGRDVDLEQLEQ--------- 110

  Fly    90 NETC-QRWIYNYDFGFRSMNAELNWVCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAVI 153
             |.| ..|.|:.|....::..|.:.||.|.:||.:..|.|::|.|:|:|..|.|.||.||...:.
Mouse   111 -ENCLDGWEYDKDIFLSTIVTEWDLVCKDDWKAPLTTSFFYVGVLLGSFISGQLSDRFGRKNILF 174

  Fly   154 L--ANQCGFVGDFLTTYASNLVQFAIFRCISGLAATANYYLMFILVLEYLAPKLRNMAISGTLGI 216
            |  |...||  .|:..::.|...|.:...:.|:...:||...|:|..|.|:..:|  .|..|||:
Mouse   175 LTMAMHTGF--SFIQVFSVNFEMFTLLYTLVGMGHISNYVAAFVLGTEMLSKSVR--IIFATLGV 235

  Fly   217 C--FCLGALVAPWLSVLAGNWRIYLTCSALLQLVVALFYFVVQESAQWLITRTNVEGAIARLKHI 279
            |  |..|.:|.|..:.....||..|....|..::....::.:.||.:|||::..::.|...::..
Mouse   236 CIFFAFGFMVLPLFAYFIREWRRLLLAITLPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKA 300

  Fly   280 AHFNGMEVKAADFEAFRRNCIVKRKL---SNQPEQTAGIFDLLRTPNLRKVSLLVVFTFMLTSLS 341
            |..||:...:..|:....|     ||   |::..|:..|:||:||||:|.::::.:..::..|:.
Mouse   301 AKINGIVAPSTIFDPSETN-----KLQDDSSKKPQSHHIYDLVRTPNIRILTIMSIILWLTISVG 360

  Fly   342 FNTISRNVEGMGLSPFVVFSLFAVVVPPSGFIQGLLQSRVGRKATAFLAMLCTGLLSCALGVALS 406
            :..:|.:...:..:.:|...|.|.|..|:..:..||...|.|:.:...::...|  |..|.|.|.
Mouse   361 YFGLSLDTPNLNGNIYVNCFLLAAVEVPAYVLAWLLLQHVSRRYSMAGSLFLGG--SVLLLVQLV 423

  Fly   407 TEGAQKNVTLLLAFALPMRLGISMCYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIH 471
            ........|.|:...   :.||:..|::...:.:||.||.||:.|:.....|:...|.:|||.::
Mouse   424 PSDLHYLSTTLVMVG---KFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVY 485

  Fly   472 LGTKLAAAPSLILALLLLTASGCTLMLPETNNRQLPITL 510
            ||......|.:::..|.:..:..||..||::...||.|:
Mouse   486 LGAYDRRLPYILMGSLTILTAIITLFFPESSGVSLPETI 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	139/546 (25%)
Slc22a21	NP_062697.1	2A0119	12..523	CDD:273328	139/546 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	532..564