Protein Alignment CG14857 and SLC22A17

DIOPT Version :10

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_065105.3
• Gene: SLC22A17 / 51310
• HGNCID: 23095
• Length: 649
• Species: Homo sapiens
• Alignment Length: 584
• Identity: 148/584 - (25%)
• Similarity: 228/584 - (39%)
• Gaps: 111/584 - (19%)

  Fly     1 MDFDQILEKCGSAGRYQYLMILLLGYIAFTTTVHYYSQNIIGFVPQHWCYHEAL----------E 55
            :.|:.:|.:.|:.|..|.|.:.|.........:...|..|....|...|::.|.          .
Human    78 LSFEALLAQVGALGGGQQLQLGLCCLPVLFVALGMASDPIFTLAPPLHCHYGAFPPNASGWEQPP 142

  Fly    56 NRSFEEI--AAIYAPFGKEASCTRLDKIEGDRVTVSNETCQRWIYNYDFGFRSMNAELNW--VCN 116
            |.|...:  ||:.|......:.:......|......|...:.|.|| .....:.||...|  ||:
Human   143 NASGVSVASAALAASAASRVATSTDPSCSGFAPPDFNHCLKDWDYN-GLPVLTTNAIGQWDLVCD 206

  Fly   117 DAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAVI-----LANQCGFVGDFLTTYASNLVQFA 176
            ..::..:.|.||.||...|....|...||.|| |.::     |...||..|    ..|.:.....
Human   207 LGWQVILEQILFILGFASGYLFLGYPADRFGR-RGIVLLTLGLVGPCGVGG----AAAGSSTGVM 266

  Fly   177 IFRCISGLAATANYYLMFILVLEYLAPKLR-NMAISGTL----GICFCLGALVAPWLSVLAGNWR 236
            ..|.:.|.........::::.||...|..| .:|::|.|    |....||      |::::.:||
Human   267 ALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFLFLG------LALVSKDWR 325

  Fly   237 IYLTCSALLQLVVALFY-----FVVQESAQWLITRTNVEGAIARLKHIAHFN-------GMEVKA 289
             :|........::.|||     |:  |||:|||.:..:|.|.:.|:.:|..|       |.|.:.
Human   326 -FLQRMITAPCILFLFYGWPGLFL--ESARWLIVKRQIEEAQSVLRILAERNRPHGQMLGEEAQE 387

  Fly   290 ADFEAFRRNCIVKRKLSNQPEQTAGIF-DLLRTPNLRKVSLLVVFTFMLTSLSFNTISRNVE--- 350
            | .:.....|.:       |..::..| .||...|:.|..|::.||        |.|:..:.
Human   388 A-LQDLENTCPL-------PATSSFSFASLLNYRNIWKNLLILGFT--------NFIAHAIRHCY 436

  Fly   351 ---GMGLSP--FVVFSLFAVVVPPSG-------FIQGLLQSRVGRKATAFLAMLCTGLLSCA-LG 402
               |.|.||  |.:.||.|     ||       |: |:...|.||:....|:|..||:.|.. ||
Human   437 QPVGGGGSPSDFYLCSLLA-----SGTAALACVFL-GVTVDRFGRRGILLLSMTLTGIASLVLLG 495

  Fly   403 V------ALSTEGAQK-------NVTLLLAFALPMRLGI--SMCYTVTSQ-FASELLPTCVRSRG 451
            :      ...|..||:       |...:..|::   ||:  |....:.|. .|:|::||.||.||
Human   496 LWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSV---LGLFSSQAAAILSTLLAAEVIPTTVRGRG 557

  Fly   452 IAAV-HLAAAGASFVSPYLIHLGTKLAAAPSLILALLLLTASGCTLMLPETNNRQLPITLADGE 514
            :..: .|.|.|........:|:|.. |....::||...|......::||||..:.||..|.|||
Human   558 LGLIMALGALGGLSGPAQRLHMGHG-AFLQHVVLAACALLCILSIMLLPETKRKLLPEVLRDGE 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	142/567 (25%)
SLC22A17	NP_065105.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..70
		MFS_SLC22A17	174..605	CDD:341003	120/471 (25%)