Protein Alignment CG14857 and slc22a15

DIOPT Version :10

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: XP_031751719.1
• Gene: slc22a15 / 448510
• XenbaseID: XB-GENE-959503
• Length: 560
• Species: Xenopus tropicalis
• Alignment Length: 583
• Identity: 133/583 - (22%)
• Similarity: 239/583 - (40%)
• Gaps: 82/583 - (14%)

  Fly     1 MDFDQILEKCGSAGRYQ-YLMILLLGYIAFTTTVHYYSQNIIGFV-PQHWCYHEALENRSFEEIA 63
            |:.:..|:..|..|.|| ||..||...:...:........|:|.. |.||.......|.|..:
 Frog    27 MEVEGALKLVGEMGIYQIYLSFLLAVLLQLYSATEAIIITILGATPPYHWMNDSLTANGSRGK-- 89

  Fly    64 AIYAPFGKEASCTRLDKIEGDRVTVSNETCQRWIYNYDFGFRSMNAELNWVCNDAYKARIGQSLF 128
                .:|.:...      ||:...|.          :|..|.|:.:|...|...||:..:..|::
 Frog    90 ----QYGSQLPA------EGEHGHVV----------FDGNFTSIVSEWFLVGGAAYEVSVSSSVY 134

  Fly   129 FLGSLMGTFTFGVLGDRIGRVRAVILANQCGFVGDFLTTYASNLVQFAIFRCISGLAATANYYLM 193
            |.|.|:|..:||.|.||.||....:.......|...:.........|.:.|.:.|:.......:.
 Frog   135 FGGVLIGVISFGQLSDRFGRKPVYVTGLALEVVFAVMNALTPIFPLFLLTRFLVGVMNGGMSLVA 199

  Fly   194 FILVLEYLAPKLRNMAISGTLG-ICFCLGALVAPWLSVLAGNWRIYLTCSALLQLVVALFYFVVQ 257
            |:|:.|.:....  .|.:|:|| :||.:|......:.....:||:......:....|......:.
 Frog   200 FVLLNECIGASY--WAAAGSLGSLCFAVGIAQFALIGYFIRSWRLLALLVNVQGAAVLALSLCIP 262

  Fly   258 ESAQWLITRTNVEGAIARLKHIAHFNGMEVKAADFEAFRRNCIVKRKLSN---QPEQ-----TAG 314
            ||.:||    :.:|   ||:        |.:.:.....|||   :||:::   .|.|     :|.
 Frog   263 ESPRWL----HAQG---RLR--------EAQESLLSLGRRN---RRKVTSFTLCPRQKDSAHSAN 309

  Fly   315 IFDLLRTPNLRKVSLLVVFTFMLTSLSFNTISRNVEGMGLSPFVVFSLFAVV-VPPSGFIQGLL- 377
            |..:.....||:.:|::::.:.:.||.:..::.:...:|...::..:|..:. :|.......|:
 Frog   310 ILTIYSNAILRQRTLIMMWVWFVCSLVYYGLTLSSGDLGGDIYLNLALSGLAELPAYPLCMYLIN 374

  Fly   378 QSRVGRKATAFLAMLCTGLLSCALGVALSTEGAQKNVTLLLAFALPM--RLGISMCYTVTSQFAS 440
            ..||||:. :....||.|..:|.|.:.:..:.....:::|.:..|.:  :|.||..:.:...::|
 Frog   375 HKRVGRRG-SLAGFLCVGGGACLLIMLVPGKTGSGPLSVLNSQTLSLLGKLNISAAFNIVYIYSS 438

  Fly   441 ELLPTCVRSRGIAAVHLAAAGASFVSPYLIHLGTKLAAAPSLILALLLLTASGCTLMLPETNNRQ 505
            ||.|||||:.|:....:.:.....::|::..|.....|.|.::.....::|...:|:||||.:..
 Frog   439 ELYPTCVRNLGMGVCSMFSRIGGIIAPFIPALRFAHWALPFIVFGAAGVSAGLLSLLLPETLSAP 503

  Fly   506 LPITLADGEAFGKGESMLSFDCWRRHDDDVSKEATEEVRLHQ--------LNGQTKSETEAEV 560
            ||.||||          |....:||.:.|      .|..||:        .||.::.:.|.|:
 Frog   504 LPETLAD----------LRGAPYRRLEPD------GEAMLHRPQAELGAFTNGSSEEDEEEEL 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	116/512 (23%)
slc22a15	XP_031751719.1	MFS	90..497	CDD:475125	95/443 (21%)