DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14857 and CG6356

DIOPT Version :9

Sequence 1:	NP_650392.1	Gene:	CG14857 / 41791	FlyBaseID:	FBgn0038262	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	NP_651240.1	Gene:	CG6356 / 42893	FlyBaseID:	FBgn0039178	Length:	570	Species:	Drosophila melanogaster

Alignment Length:	546	Identity:	131/546 - (23%)
Similarity:	224/546 - (41%)	Gaps:	68/546 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LEKCGSAGRYQYLMILLLGYIAFTTTVHYYSQNIIGFVP-QHWCYHEALENRSF-----EEIAAI 65
            ||..||.|.:.:.:..|..........|..|..::|.:| ..||....|::.::     .||.|.
  Fly    28 LEVVGSGGAFVWAIFFLCVTPNILNGFHVSSYTLLGHLPDDQWCGIPELQDTNWTHAQKREIVAK 92

  Fly    66 YAPFGKEASCTRLDKIEGDRVTVSNETCQRWIYN-----------------YDFGFRSMNAELNW 113
            ....|   .||..|...|....:|.|....:..:                 ::|.........:|
  Fly    93 GLDSG---GCTVWDWNYGHLAKMSYEAALNYTGHLTQISPPAEVSCRVKGQHEFAHPETTFVADW 154

  Fly   114 --VCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAVILANQCGFVGDFLTTYASNLVQFA 176
              .|:.:.:....|....||...|:|:||:|.|:.||..:..|......||.|..|::.....|.
  Fly   155 DLTCDRSIQRTSAQVSISLGKFCGSFSFGILADKFGRKSSFTLGAAFFIVGSFFCTFSPWYSLFL 219

  Fly   177 IFRCISGLAATANYYLMFILVLEYLAPKLR---NMAISGT----LGICFCLGALVAPWLSVLAGN 234
            ..|...|.|::..:|..|.:::|.:..|.|   ::|.|.:    :.|...:|.::.||..:
  Fly   220 AGRFALGAASSGLFYPAFTMIVENICLKHRSWMSIAFSASYPVGMIILAIVGYVIQPWRHL---- 280

  Fly   235 WRIYLTCSALLQLVVALFYFVVQESAQWLITRTNVEGAIARL-KHIAHFNGMEVKAADFEAFRRN 298
             ::.||..:||   :.|..:::.||.:||||....:.....| :..:|:......||..:
  Fly   281 -QLALTIPSLL---LILNCYLMSESPRWLITNQRYDRVYKILFRQPSHYQIQPAVAAPSQ----- 336

  Fly   299 CIVKRKLSNQPEQ------------TAGIFDLLRTPNLRKVSLLVVFTFMLTSLSFNTISRNVEG 351
             :...|.|.:||:            ...|.:|.....:|::.....|.|.:||||:...:.|...
  Fly   337 -VASDKKSLEPEEGFSFGQKLKNGPLKSIIELYANSKVRRMIFASYFMFCVTSLSYYVTALNAAN 400

  Fly   352 MGLSPFVVFSLFAVVVPPSGFIQGLLQSRVGRKATAFLAMLCTGLLSCALGVALSTEGAQKNVTL 416
            :.:|.::......:|..||..:..::....||:.|.....|.|| :|..|.:|:..    .:.|.
  Fly   401 LSVSRYLYIIGTGLVDIPSYLVPVIMLRFTGRRLTTMFLFLWTG-VSLLLVLAVPA----GSTTW 460

  Fly   417 LLAFALPMRLGISMCYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIH-LGTKLAAAP 480
            ::|||:..|.|||..|:|.:.:.:||.||.:|:..:......|...|..:||::. ||......|
  Fly   461 IVAFAMLGRFGISATYSVVTLYTAELYPTQIRNSALGTCSTFAHVGSISAPYVVDVLGALGWYIP 525

  Fly   481 SLILALLLLTASGCTLMLPETNNRQL 506
            :.|....:|.|...||.||||...:|
  Fly   526 TTICGCCVLVAGLLTLTLPETGTGKL 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	129/542 (24%)
CG14857	NP_650392.1	MFS	126..470	CDD:119392	91/363 (25%)
CG6356	NP_651240.1	MFS	167..544	CDD:119392	100/395 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458476
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I1789
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	5	4.990