DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14857 and Orct

DIOPT Version :9

Sequence 1:	NP_650392.1	Gene:	CG14857 / 41791	FlyBaseID:	FBgn0038262	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	NP_001262908.1	Gene:	Orct / 42891	FlyBaseID:	FBgn0019952	Length:	548	Species:	Drosophila melanogaster

Alignment Length:	590	Identity:	152/590 - (25%)
Similarity:	253/590 - (42%)	Gaps:	77/590 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFDQILEKCGSAGRYQ----YLM--------------ILLLGYIAFTTTVHYYSQNIIGFVPQH 47
            |.:|.::...|..|.||    ||:              :.||....|...:.|.:.:|....|..
  Fly     1 MGYDDVITHLGEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYENGSIYELSPHL 65

  Fly    48 WCYHEALENRSFEEIAAIYAPFGKEASCTRLD------KIEGDRVTVSNE--TCQRWIYNYDFGF 104
            |       |.|:.|          ...|:..|      .:.|.....|||  ||..::|:.....
  Fly    66 W-------NLSYPE----------NERCSYYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSKYL 113

  Fly   105 RSMNAELNWVCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAVILANQCGFVGDFLTTYA 169
            .|...|.|.||:.:..:....|||.||.|:|:..||.:.|::||......:.....:...|...|
  Fly   114 NSAVTEWNLVCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVA 178

  Fly   170 SNLVQFAIFRCISGLAATANYYLMFILVLEYLAPKLRNMAISGTLGICFCLGALVAPWLSVLAGN 234
            .....:.|.|.|.|...:..:.:.:::.||.:....|..| ...:.:.|.:|.::....:....:
  Fly   179 PEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFA-GVAMQMFFSVGFMLTAGFAYFIHD 242

  Fly   235 WR---IYLTCSALLQLVVALFYFVVQESAQWLITRTNVEGAIARLKHIAHFNGMEVKAADFEAFR 296
            ||   |.:|...||.|   .:|:::.|||:||:.:...:.|...::..|..|.:||....:|...
  Fly   243 WRWLQIAITLPGLLFL---CYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLV 304

  Fly   297 RNCIVKRK----LSNQPEQTAGIFDLLRTPNLRKVSLLVVFTFMLTSLSFNTISRNVEGMGLSPF 357
            .....|:|    .::||..|  :|||||.||||:.:||:.|.:.:.|..:..:|.|...:|.:..
  Fly   305 DEVAEKKKQDEMAASQPAAT--VFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQL 367

  Fly   358 VVFSLFAVVVPPSGFIQGLLQSRVGRKATAFLAMLCTGLLSCALGVALSTEGAQKNVT-LLLAFA 421
            |.|.:...|..|...:.....:|.||:     ::||..::...:.: |:|.....::. |::|.|
  Fly   368 VNFMISGAVEIPGYTLLLFTLNRWGRR-----SILCGTMMVAGISL-LATIFVPSDMNWLIVACA 426

  Fly   422 LPMRLGISMCYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIHLGTKLAAAPSLILAL 486
            :..:|.|:..|.....|::|..||.||:.|:.|..:.|.....::|||..||......|.:|...
  Fly   427 MIGKLAITSSYGTIYIFSAEQFPTVVRNVGLGASSMVARVGGILAPYLKLLGEIWRPLPLIICGA 491

  Fly   487 LLLTASGCTLMLPETNNRQLPITLADGEAFGKGESMLSFDCWRRHDDDVSKEATEEVRLHQLNGQ 551
            |.|||...:|:||||.|:.:|.|:.|||.|||              ....:|..||....:|:|.
  Fly   492 LSLTAGLLSLLLPETLNKPMPETIEDGENFGK--------------KPAPQETAEEGGTQELSGM 542

  Fly   552 TKSET 556
            ...::
  Fly   543 LNGKS 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	138/531 (26%)
CG14857	NP_650392.1	MFS	126..470	CDD:119392	92/351 (26%)
Orct	NP_001262908.1	2A0119	11..514	CDD:273328	138/531 (26%)
Orct	NP_001262908.1	MFS	135..491	CDD:119392	97/367 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458404
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I1789
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	5	4.990