DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14857 and CG6006

DIOPT Version :9

Sequence 1:	NP_650392.1	Gene:	CG14857 / 41791	FlyBaseID:	FBgn0038262	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	NP_001097812.1	Gene:	CG6006 / 41962	FlyBaseID:	FBgn0063649	Length:	603	Species:	Drosophila melanogaster

Alignment Length:	535	Identity:	126/535 - (23%)
Similarity:	223/535 - (41%)	Gaps:	65/535 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 DQILEKCGSAGRYQYLMILLLGYIAFTTTVHYYSQNIIGFVPQHWCYHEA-LENRSFEEIAAIYA 67
            |.|.:..|..|::|.||.:||.......|.|..|..........||...| |::.   .:|....
  Fly    83 DVIGDLMGHYGKWQLLMTVLLSLFQVPNTFHISSSIYQAANKDFWCQRPAQLQHM---PVATWRN 144

  Fly    68 PFGKEASCTRLDKIEGDRVTVSNET------------------CQRWIY--NYDFGFRSMNAELN 112
            ..|...:|.|.:.|:..:  |||||                  |::|.|  |.:.| .:..::.:
  Fly   145 LSGSVDNCRRWEGIDWSQ--VSNETTLPSDWKTPAEMDKKLVACEKWEYETNDNVG-NTWTSQWD 206

  Fly   113 WVCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAVILANQCGFVGDFLTTYASNLVQFAI 177
            .||...:...:.:..|.||...|....|.|.|:.||...:.::.....:........|:...:..
  Fly   207 LVCEKEHLKNVAEMFFLLGVATGGIISGYLSDKFGRKTMLFISAVLQTIFGLWLYICSSFELYLT 271

  Fly   178 FRCISGLAATANYYLMFILVLEYLAPKLRNMAISGTLGIC-FCLGALVAPWLSVLAGNWRIYLTC 241
            .|.:.||.:.:..|...||.:||:..|.|  .|:|...:. ..:..::...|:.|..:::....|
  Fly   272 LRALLGLVSVSVTYSGLILAIEYVDGKWR--TIAGMYNLFPLPISYMIISGLAYLTQDYQRLQLC 334

  Fly   242 SALLQLVVALFYFVVQESAQWLITRTNVEGAIARLKHIAHFNGMEVKAADFEAFRRNCIVKRKLS 306
            ..:..:.:...:|||.||.:||:.:..::.....::..|.|||.:: .||::.         ...
  Fly   335 IGIPGIFLCFLWFVVPESPRWLLVKGRIDEVRRIIEAAAKFNGRQL-PADYQL---------TPP 389

  Fly   307 NQPEQTAGIFDLLRTPNLRKVSLLVVFTFMLTSLSFNTISRNVEGMGLSPFVVFSLFAVVVPPSG 371
            .|...|..:..|.|:..||::|:.....:...:|.:..|..|:...|.:.::..:|..:|..|:.
  Fly   390 TQESSTQDVTYLFRSSYLRRISICFFCIWFTMNLVYYGIILNMSSFGGNVYLNSALAGLVEIPAI 454

  Fly   372 FIQGLLQSRVGRKATAFLAMLCTGLLSCALGVALSTEGAQKNVTLLLAFALPMRLGISMCYTVTS 436
            .:...:.::||:|......::|.|:..|...:   |||....:.|.:.|.:..:..||...|:..
  Fly   455 AVAMYIITKVGKKWLFCATLICAGVACCCAAI---TEGHADLLWLKITFLMMGKFTISAGNTIMP 516

  Fly   437 QFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIHLGTKLAAAPSLI------LALLLLTA---- 491
            .:.:||.||.:|:.|:.|.::||..|..::|||           ||:      |.:.||||
  Fly   517 VYTAELYPTPIRNVGVGACNVAAGLALILTPYL-----------SLLNKIEGHLLMTLLTAWSIF 570

  Fly   492 -SGCTLMLPETNNRQ 505
             ....|.||||..||
  Fly   571 GGFVVLFLPETAVRQ 585

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	124/528 (23%)
CG14857	NP_650392.1	MFS	126..470	CDD:119392	78/344 (23%)
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	120/522 (23%)
CG6006	NP_001097812.1	MFS	222..579	CDD:119392	87/382 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I1789
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	4	4.060