Protein Alignment CG14857 and slc22a2

DIOPT Version :10

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_998315.1
• Gene: slc22a2 / 406424
• ZFINID: ZDB-GENE-040426-2167
• Length: 562
• Species: Danio rerio
• Alignment Length: 593
• Identity: 139/593 - (23%)
• Similarity: 247/593 - (41%)
• Gaps: 101/593 - (17%)

  Fly     3 FDQILEKCGSAGRYQYLMILLLGYIAFTTTVHYYSQNIIGFVPQHWCYHE-----------ALEN 56
            |::|||:.|:.||.|..:......::...:..|......||.|:|||...           :|::
Zfish     4 FEEILEEAGTFGRSQIRIFCTFCLVSIPFSFVYVGIVFQGFTPEHWCRDPGVSEIRERCGWSLQD 68

  Fly    57 RSFEEIAAIYAPFGKEAS-CTRLDKIEGDRVTVSNE-----------------TC-QRWIYNYDF 102
            .....:..|....|...| |.|.| ::.:...:|.|                 :| ..|.|:| .
Zfish    69 ARRATVPLINGSSGASYSQCGRFD-VDWNATGLSCENPDGDFNQSQLSVMPMMSCVDGWEYDY-V 131

  Fly   103 GFRSMNAELNWVCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAVILANQCGFVG--DFL 165
            |.:|...|.:.||.||:...:.|:...:|.|:|:...|.|.|:.||:::.::.|  .|:|  ..|
Zfish   132 GRQSFVTEFDLVCGDAWYVDMFQATLSIGFLVGSIAIGYLADKYGRMKSFLMTN--FFIGVTGIL 194

  Fly   166 TTYASNLVQFAIFRCISGLAATANYYLMFILVLEYLAPKLRNMAISGTLGICFCLGALVAPWLSV 230
            ...:.|.:...:||.:.|......:.:.::|:.|.:....|. .:..|..:.|.:|.|:.|.|:.
Zfish   195 VATSPNYISLLVFRALFGFGVKGGWMVGYVLITELVGVDHRR-TVGVTYQLFFSMGILLLPLLAY 258

  Fly   231 LAGNWRIYLTCSALLQLVVALFYFVVQESAQWLITRTNVEGAIARLKHIAHFNGMEVKAADFEAF 295
            ...|||.......:..:....:|:.:.||.:||:|:..:..|:...|.||..|
Zfish   259 FITNWRWLQVVFTVPYICFLTYYWFIPESPRWLLTQNKIAEAVEITKSIAKEN------------ 311

  Fly   296 RRNCIVKRKLSNQPE----------QTAGIFDLLRTPNLRKVSLLVVFTFMLTSLSFNTISRNVE 350
                  ::.||.:.|          .||...||.:|..||..:.::.|.:..:::.:..:...:.
Zfish   312 ------RKTLSKKIETLKDDNIDSGSTASFMDLFKTAKLRTYTFILSFNWFTSAVVYQGLIMRLG 370

  Fly   351 GMGLSPFVVFSLFAVVVPPSGFIQGLLQSRVGRK---ATAFL----AMLCTGLLSCALGVALSTE 408
            .:|.:.:|.|.:..:|..|:.|:..|...|:||:   |||.:    |.|.|..:..::
Zfish   371 ILGGNVYVDFLISGIVELPAAFLILLTIERIGRRLPFATANIVAGAACLITAFIPDSM------- 428

  Fly   409 GAQKNVTLLLAFALPMRLGISMCYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIHLG 473
                 ..|..|.|...||||:|.:.:.....:||.||.:|:.|::...........|:|:|::
Zfish   429 -----FWLKSAVACVGRLGITMAFEMVVFVNTELYPTVIRNLGVSVCSTLCDVGGIVAPFLLY-- 486

  Fly   474 TKLAA----APSLILALLLLTASGCTLMLPETNNRQLPITLADGEAFGKG----------ESMLS 524
             :||.    .|.:|...|...|.|..|:||||....||.|:.|.|...:.          |::::
Zfish   487 -RLAVIWLELPLIIFGALAFVAGGLVLLLPETKGVPLPETIDDIEHPNRNKENPQQSQQLENLMT 550

  Fly   525 FDCWRRHD 532
            .|..:..|
Zfish   551 SDVTKNKD 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	129/550 (23%)
slc22a2	NP_998315.1	MFS_SLC22A1_2_3	116..515	CDD:340937	103/435 (24%)