Protein Alignment CG14857 and SLC22A

DIOPT Version :9

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Alignment Length: 560
• Identity: 135/560 - (24%)
• Similarity: 244/560 - (43%)
• Gaps: 67/560 - (11%)

  Fly     4 DQILEKCGSAGRYQYLMILL-----LGYIAFTTTVHYYSQNIIGFVPQHWC-----------YHE 52
            |.||:..|..||:|.::.||     :.:..|:.|..:.:..:     .|.|           |:|
  Fly    28 DAILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATV-----THRCSVEECDLPGSNYYE 87

  Fly    53 ALENRSFEEIAAIYAPFGKEA-SCTR------------LDKIEGDRVTVSNETCQRWIYNYDFGF 104
            ...|.|..:       .||:. ||.|            :|....|..|.:.|.|.    :.:|.|
  Fly    88 PHTNWSIPK-------NGKDLDSCNRYTNSELPQWNHSVDICSADHFTKNKEACA----HNEFVF 141

  Fly   105 R----SMNAELNWVCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAVILANQCGFVGDFL 165
            |    :::.:....|:|.:|..:..::..||...|....|.:.||.||..::.|....|.|...:
  Fly   142 RDDEVTISNDFGIFCDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVLGVI 206

  Fly   166 TTYASNLVQFAIFRCISGLAATANYYLMFILVLEYLAPKLRNMAISGTLGICFCLGALVAPWLSV 230
            .:::.:...|.:|..:..:.::..|...|::.:|.:.||.|.:|.| .:.:.:.:|.::....:.
  Fly   207 RSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACS-VITVFYAVGEVLLAMSAK 270

  Fly   231 LAGNWRIYLTCSALLQLVVALFYFVVQESAQWLITRTNVEGAIARLKHIAHFNGMEVKAADFEAF 295
            ...:|||.|..:....|::..:::::.||.:||:::...|.|...|:..||.|..|:..:..:
  Fly   271 AFHDWRILLRITYGPSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRELPESVLD-- 333

  Fly   296 RRNCIVKR-KLSNQPEQTAGIFDLLRTPNLR--KVSLL-VVFTFMLTSLSFNTISRNVEGMGLSP 356
             :..:..| ||....|....|.:..:....|  ..||. :|...:...||.|.:.  ::|   ..
  Fly   334 -KLVLANRDKLQQSSESRFPIREAFKNFKWRIANCSLCWIVHVLVYYGLSLNVVL--LDG---DK 392

  Fly   357 FVVFSLFAVVVPPSGFIQGLLQSRVGRKATAFLAMLCTGLLSCALGVALSTEGAQKNVTLLLAFA 421
            :..|:..|:|..|..|:..|:..|.||:.:....||.:||  |.:|...:  ||.:.|..|:.|
  Fly   393 YNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGL--CCIGTIFT--GADQPVLQLVLF- 452

  Fly   422 LPMRLGISMCYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIHLGTKLAAAPSLILAL 486
            |..:|.|:..:.|...||||:.||.:|:..::...:.....|.::|....|....|.||:::.|.
  Fly   453 LVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFAG 517

  Fly   487 LLLTASGCTLMLPETNNRQLPITLADGEAFGKGESMLSFD 526
            ..:.:...||..|||.|..||.|:.:.:|.|..:...|.|
  Fly   518 AAIVSGLLTLFFPETTNVVLPTTVQEADAIGVKKQSKSKD 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	127/534 (24%)
		MFS	126..470	CDD:119392	84/347 (24%)
SLC22A	NP_649370.1	2A0119	35..540	CDD:273328	127/534 (24%)
		MFS	146..530	CDD:119392	94/397 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458501
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I1789
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.990