Protein Alignment CG14857 and SLC22A

DIOPT Version :10

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Alignment Length: 560
• Identity: 135/560 - (24%)
• Similarity: 244/560 - (43%)
• Gaps: 67/560 - (11%)

  Fly     4 DQILEKCGSAGRYQYLMILL-----LGYIAFTTTVHYYSQNIIGFVPQHWC-----------YHE 52
            |.||:..|..||:|.::.||     :.:..|:.|..:.:..:     .|.|           |:|
  Fly    28 DAILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATV-----THRCSVEECDLPGSNYYE 87

  Fly    53 ALENRSFEEIAAIYAPFGKEA-SCTR------------LDKIEGDRVTVSNETCQRWIYNYDFGF 104
            ...|.|..:       .||:. ||.|            :|....|..|.:.|.|.    :.:|.|
  Fly    88 PHTNWSIPK-------NGKDLDSCNRYTNSELPQWNHSVDICSADHFTKNKEACA----HNEFVF 141

  Fly   105 R----SMNAELNWVCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAVILANQCGFVGDFL 165
            |    :::.:....|:|.:|..:..::..||...|....|.:.||.||..::.|....|.|...:
  Fly   142 RDDEVTISNDFGIFCDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVLGVI 206

  Fly   166 TTYASNLVQFAIFRCISGLAATANYYLMFILVLEYLAPKLRNMAISGTLGICFCLGALVAPWLSV 230
            .:::.:...|.:|..:..:.::..|...|::.:|.:.||.|.:|.| .:.:.:.:|.::....:.
  Fly   207 RSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACS-VITVFYAVGEVLLAMSAK 270

  Fly   231 LAGNWRIYLTCSALLQLVVALFYFVVQESAQWLITRTNVEGAIARLKHIAHFNGMEVKAADFEAF 295
            ...:|||.|..:....|::..:::::.||.:||:::...|.|...|:..||.|..|:..:..:
  Fly   271 AFHDWRILLRITYGPSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRELPESVLD-- 333

  Fly   296 RRNCIVKR-KLSNQPEQTAGIFDLLRTPNLR--KVSLL-VVFTFMLTSLSFNTISRNVEGMGLSP 356
             :..:..| ||....|....|.:..:....|  ..||. :|...:...||.|.:.  ::|   ..
  Fly   334 -KLVLANRDKLQQSSESRFPIREAFKNFKWRIANCSLCWIVHVLVYYGLSLNVVL--LDG---DK 392

  Fly   357 FVVFSLFAVVVPPSGFIQGLLQSRVGRKATAFLAMLCTGLLSCALGVALSTEGAQKNVTLLLAFA 421
            :..|:..|:|..|..|:..|:..|.||:.:....||.:||  |.:|...:  ||.:.|..|:.|
  Fly   393 YNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGL--CCIGTIFT--GADQPVLQLVLF- 452

  Fly   422 LPMRLGISMCYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIHLGTKLAAAPSLILAL 486
            |..:|.|:..:.|...||||:.||.:|:..::...:.....|.::|....|....|.||:::.|.
  Fly   453 LVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFAG 517

  Fly   487 LLLTASGCTLMLPETNNRQLPITLADGEAFGKGESMLSFD 526
            ..:.:...||..|||.|..||.|:.:.:|.|..:...|.|
  Fly   518 AAIVSGLLTLFFPETTNVVLPTTVQEADAIGVKKQSKSKD 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	127/534 (24%)
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	97/407 (24%)