Protein Alignment CG14857 and Slc22a14

DIOPT Version :9

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_001032838.1
• Gene: Slc22a14 / 382113
• MGIID: 2685974
• Length: 629
• Species: Mus musculus
• Alignment Length: 525
• Identity: 135/525 - (25%)
• Similarity: 229/525 - (43%)
• Gaps: 45/525 - (8%)

  Fly     3 FDQILEKCGSAGRYQYLMILLLGYIAFTTTVHYYSQNIIGFVPQHWC----YHEALENRSFEE-- 61
            |..:::..|..|.:|:.:::|....:..:|...:|.:.:....:.:|    ..|...|.:.:|
Mouse    51 FASVMDAIGEFGTFQWRLVVLTFIPSILSTFFIFSHHFLLTAQRPYCNTSWILEVGPNLTEDEQL 115

  Fly    62 -IAAIYAPFGKEASCTRLDKIEGDRVTVSN------ETCQ-RWIYNYDFGFRSMNAELNWVCNDA 118
             :....||.|...:|.....:..|..::.:      |||: .|||.:.. .||:..|.:.||.:.
Mouse   116 NLTLPRAPNGSFLTCLMYIPVPWDLDSIIHFGLNYTETCKFGWIYPFAH-TRSLINEFDLVCGNE 179

  Fly   119 YKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAVILANQCGF-VGDFLTTYASNLVQFAIFRCIS 182
            .....|.::|..|.|.|:..||.|.|::||. .:||.:..|| :..|.|.:.|:..|:..||...
Mouse   180 PNKENGLTVFLSGVLTGSLLFGFLSDKLGRY-PIILLSLLGFLIFGFGTAFVSSFYQYLFFRFFV 243

  Fly   183 GLAATANYYLMFILVLEYLAPKLRNMAISGTLGICF-CLGALVAPWLSVLAGNWRIYLTCSALLQ 246
            ..|:.........||:|:|..:.|..|:  .|...| .:|.::...|:....:||:......:..
Mouse   244 AQASVGYAICSVSLVMEWLVGEHRAQAV--ILQHSFLTIGVILLTGLAYKVVHWRLLCLLGGMPM 306

  Fly   247 LVVALFYFVVQESAQWLITRTNVEGAIARLKHIAHFNGMEVKAADFEAFRRNCIVKRKLSNQPEQ 311
            ..:....:|::||.:||:.|..||.|...|.:.|..|...:..        |.:.:.::|.:...
Mouse   307 FPLICNIWVLRESPRWLMVRGKVEEAKKVLCYAAEVNKKTIPL--------NLLNELQISGKKVA 363

  Fly   312 TAGIFDLLRTPNLRKVSLLV-VFTFMLTSLSFNTISRNVEGMGLSPFVVFSLFAVVVPPSGFIQG 375
            .|.|.|.....:|.||.|.: ...|.::.:|| |::..:...||..:.|..:.::|..|:.....
Mouse   364 KASILDFCTNQHLFKVVLAIGCVWFTVSYISF-TLNLKMNDFGLDVYFVQMVRSIVAVPARLCCI 427

  Fly   376 LLQSRVGRK-ATAFLAMLCTGLLSCALGVALSTEGAQKNV-TLLLA-FALPMRLGISMCYTVTSQ 437
            :|....||| |......|.|.:  |...:.|..|.....: ||:|| |::...|.|...||
Mouse   428 ILLEYFGRKWALNLTLFLVTSM--CLFLLFLPQEPKSTIILTLMLAEFSMAGTLSIFFIYT---- 486

  Fly   438 FASELLPTCVRSRGIAAVHLA-AAGASFVSPYLIHLGTKLAAAPSLILALLLLTASGCTLMLPET 501
              :|||||.:||.|:..|.|| .|||  :|...|...|| ...|.....|..:.|...:.::|||
Mouse   487 --AELLPTVLRSTGLGMVSLAWVAGA--ISSVAIFKQTK-TQLPIFFCCLCCVLALCFSSLVPET 546

  Fly   502 NNRQL 506
            .::.|
Mouse   547 GSQSL 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	134/517 (26%)
		MFS	126..470	CDD:119392	97/350 (28%)
Slc22a14	NP_001032838.1	2A0119	59..553	CDD:273328	134/517 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844083
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.030