Protein Alignment CG14857 and Slc22a20

DIOPT Version :9

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_941052.1
• Gene: Slc22a20 / 381203
• MGIID: 2685809
• Length: 556
• Species: Mus musculus
• Alignment Length: 586
• Identity: 145/586 - (24%)
• Similarity: 240/586 - (40%)
• Gaps: 61/586 - (10%)

  Fly     1 MDFDQILEKCGSAGRYQ--YLMILLL--GYIAFTTTVHYYSQNIIGFVPQHWCYHEALENRSFEE 61
            |.|..:|:..|..||:|  |..:|||  |.:|    .|.:.||.....|.|.|.|.|........
Mouse     1 MAFTDLLDALGGVGRFQLVYTALLLLPCGLLA----CHTFLQNFTAAAPPHHCQHPANYTEPTTN 61

  Fly    62 IAAIYA-------PFGKEASCTR-------LDKIEGDRVTVSNETCQ-RWIYNYDFGFRSMNAEL 111
            ::.::.       ..|....|.|       |.|.......|:.|.|: .|:|:......::..|.
Mouse    62 VSGVWLRAAIPLNQHGDPEPCRRYVEPQWALLKPNASSHGVATEGCKDGWVYDRSIFPSTIVMEW 126

  Fly   112 NWVCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAVILANQCGFVGDFLTTYASNLVQFA 176
            :.||.......:.||::..|.|:|...||.|.||:||...::.:.....|....|.|..:...:.
Mouse   127 DLVCEARTLRDLAQSIYMSGVLVGAALFGGLADRLGRKAPLVWSYLQLAVSGAATAYVGSFSAYC 191

  Fly   177 IFRCISGLAATANYYLMFILVLEYLAPKLRNMAISGTLGICFCLGALVAPWLSVLAGNWR-IYLT 240
            :||.:.|:..:........||:|::..:.|.:| ...||..|.||.|:...::.|...|| :...
Mouse   192 VFRFLMGMTFSGIILNSLSLVVEWMPTRGRTVA-GILLGFSFTLGQLILAGVAYLIRPWRWLQFA 255

  Fly   241 CSALLQLVVALFYFVVQESAQWLITRTNVEGAIARLKHIAHFNGMEVKAADF-----EAFRRNCI 300
            .||.. ||..|:.:.:.||::||:.....:.|:..|:.:|..||.:.:....     .::.::..
Mouse   256 VSAPF-LVFFLYSWWLPESSRWLLLHGKAQQAVQNLQKVAMMNGRKAEGERLTTEVVSSYIQDEF 319

  Fly   301 VKRKLSNQPEQTAGIFDLLRTPNLRKVSLLVVFTFMLTSLSFNTISRNVEGMGLSPFVVFSLFAV 365
            ...:.||      .|.||.|||.:|:|:..::..:...|:::..::.:::..|||.::|.:||.:
Mouse   320 ASVRTSN------SILDLFRTPAIRRVTCCLMGVWFSNSVAYYGLAMDLQKFGLSIYLVQALFGI 378

  Fly   366 VVPPSGFIQGLLQSRVGRKATAFLAMLCTGLLSCALGVALSTEGAQKNVTLLLAFALPMRLGISM 430
            :..|:..:.......|||:||....::..||:  .:......|..|...|:..|..........:
Mouse   379 IDIPAMLVATTTMIYVGRRATVSSFLILAGLM--VIANMFMPEDLQTLRTVQAALGKGCLASSFI 441

  Fly   431 CYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIHLGTKLAAAPSLIL-ALLLLTASGC 494
            |..:   |..||.||.:|..|:....:.|.....|:|.:..||......|.:.. |..:|.....
Mouse   442 CVYL---FTGELYPTEIRQMGMGFASVNARLGGLVAPLITTLGEISPVLPPVSFGATSVLAGMAV 503

  Fly   495 TLMLPETNNRQLPITLADGEAFGKGESMLSFDCWRRHDDDVSKEAT----EEVRLHQLNGQTKSE 555
            ...|.||.|..|..|:|..|              ||.....||..|    ||:.|.||......|
Mouse   504 ACFLTETRNVPLVETIAAME--------------RRVKQGRSKRDTEQKSEEISLQQLGASPLKE 554

  Fly   556 T 556
            |
Mouse   555 T 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	127/523 (24%)
		MFS	126..470	CDD:119392	85/349 (24%)
Slc22a20	NP_941052.1	2A0119	11..518	CDD:273328	127/523 (24%)
		MFS	138..507	CDD:119392	91/381 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	526..556		10/30 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843545
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.950