Protein Alignment CG14857 and Slc22a12

DIOPT Version :9

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: XP_038941497.1
• Gene: Slc22a12 / 365398
• RGDID: 621628
• Length: 578
• Species: Rattus norvegicus
• Alignment Length: 618
• Identity: 152/618 - (24%)
• Similarity: 264/618 - (42%)
• Gaps: 117/618 - (18%)

  Fly     1 MDFDQILEKCGSAGRYQYLM-ILLLGYIAFTTTVHYYSQNIIGFVPQHWCYHEALENRSFEEIAA 64
            |.|.::|::.|..||:|.|. :.|:..|.:.||.:.. :|....||.|.|:...|:|.:.:  |:
  Rat     1 MAFPELLDRVGGRGRFQLLQAVALVTPILWVTTQNML-ENFSAAVPHHRCWVPLLDNSTSQ--AS 62

  Fly    65 IYAPFGKEA---------------SCTRLDK-----IEGDRVTVSN------ETCQ-RWIYNYDF 102
            |...||::.               .|.|..:     ||.: .|.:|      |.|: .|:|::.
  Rat    63 IPGDFGRDVLLAVSIPPGPDQRPHQCLRFRQPQWQLIESN-TTATNWSDADTEPCEDGWVYDHS- 125

  Fly   103 GFRSMNAELNW--VCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAV----ILANQCGFV 161
            .||| .....|  ||:......:.||:|..|.|:|....|...||.||.|.:    :|.:..|.:
  Rat   126 TFRS-TIVTTWDLVCDSQALRPMAQSIFLAGILVGAAVCGHASDRFGRRRVLTWSYLLVSVSGTI 189

  Fly   162 GDFLTTYASN-LVQFAIFRCISGLAATANYYLMFILVL--------EYLAPKLRNMAISGTLG-- 215
            ...:.|:... |.:|.:...::|:........||.:||        ..|.|.|....:..|..
  Rat   190 AALMPTFPLYCLFRFLVASAVAGVMMNTASLCMFPVVLGREGYMQDPELTPSLLLAVMEWTSAQA 254

  Fly   216 --ICFCLGALVAPWLSVLAG-------NWRIYLTCSALLQLVVALFYFV-------VQESAQWLI 264
              :...|.||...:..||.|       :||       :|||.|:..:|:       :.|||:|||
  Rat   255 GPLMMTLNALGFSFGQVLTGSVAYGVRSWR-------MLQLAVSAPFFLFFVYSWWLPESARWLI 312

  Fly   265 TRTNVEGAIARLKHIAHFNGMEVKAADFEAFRRNCIVKRKLSNQP---EQTAGIFDLLRTPNLRK 326
            |...::.::..|:.:|..|..:.:|......    :::..:..:|   :..|.:..||.||.||.
  Rat   313 TVGRLDQSLRELQRVAAVNRRKAEADTLTVE----VLRSAMQEEPNGNQAGARLGTLLHTPGLRL 373

  Fly   327 ---VSLLVVFTFMLTSLSFNTISRNVEGMGLSPFVVFSLFAVVVPPSGFIQGLLQSRVGRKATAF 388
               :|:|..|.|..|   |..::.:::.:|.:.|::.:|..:|..|......||.||:||:....
  Rat   374 RTFISMLCWFAFGFT---FYGLALDLQALGSNIFLLQALIGIVDLPVKMGSLLLLSRLGRRLCQA 435

  Fly   389 LAMLCTGLLSCALGVALSTEGAQKNVTLLLAFALPMRLG-ISMCYTVTSQFASELLPTCVRSRGI 452
            .:::..||  |.|...|    ..:.:.:|.:....:.|| :...:|..:.|:|||.||.:|...:
  Rat   436 SSLVLPGL--CILANIL----VPREMGILRSSLAVLGLGSLGAAFTCVTIFSSELFPTVIRMTAV 494

  Fly   453 AAVHLAAAGASFVSPYLIHLGTKLAAAPSLILALLLLTASGCTLMLPETNNRQLPITLADGEAFG 517
            ....:||.|.:.:.|.:..||...:..|.|:..::.:.:....|:||||.|..||.|:
  Rat   495 GLGQVAARGGAMLGPLVRLLGVYGSWLPLLVYGVVPVLSGLAALLLPETKNLPLPDTI------- 552

  Fly   518 KGESMLSFDCWRRHDDDVSKEATEEVRLHQLNG 550
                           .|:.|::.::| .|.:.|
  Rat   553 ---------------QDIQKQSVKKV-THDIAG 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	143/565 (25%)
		MFS	126..470	CDD:119392	94/381 (25%)
Slc22a12	XP_038941497.1	MFS_OAT	109..541	CDD:340932	110/453 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346837
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.950