DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14857 and Balat

DIOPT Version :9

Sequence 1:	NP_650392.1	Gene:	CG14857 / 41791	FlyBaseID:	FBgn0038262	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	NP_610823.1	Gene:	Balat / 36417	FlyBaseID:	FBgn0033778	Length:	604	Species:	Drosophila melanogaster

Alignment Length:	556	Identity:	152/556 - (27%)
Similarity:	245/556 - (44%)	Gaps:	57/556 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFDQILEKCGSAGRYQYLMIL-LLGYIAFTTTVHYYSQNIIGFVPQHWC-----------YHEA 53
            ||||::|.:.||.|.||.::|. :|...|.....|.|||..|...|||:|           |.:.
  Fly     1 MDFDEVLREVGSFGLYQKVIICSVLLPAALPCAFHAYSQLFIAATPQHFCRVPELEPWTQDYVQL 65

  Fly    54 LEN------------------RSFEEIAAIYAPFGKEASCTR-----LDKIEGDRVTVSNETCQR 95
            ::|                  |::.:|.. |..:.......|     |.|::.|  |.....||.
  Fly    66 VKNLSIPRNRNGAYAECSMYSRNYTDIVR-YLEYRPPPDLLRQQAEDLLKLQPD--TTQVVPCQH 127

  Fly    96 -WIYNYDFGFRSMNAELNWVCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAVILANQCG 159
             |.|:......::..|.|.||:.::...:...:|.:|.|:|.:.||.|.|..||..:........
  Fly   128 GWHYDKSIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVDLWGRRPSFYAYLLLE 192

  Fly   160 FVGDFLTTYASNLVQFAIFRCISGLAATANYYLMFILVLEYLAPKLRNMAISGTLGICFCLGALV 224
            .:....:.:|.|...:...|.:.||...|.....::|.:|.:.|: |.:..:....|.:.||.:|
  Fly   193 IIACAASAFAWNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPE-RRVFCTIVSNIAYSLGLVV 256

  Fly   225 APWLSVLAGNWR-IYLTCSALLQLVVALFYFVVQESAQWLITRTNVEGAIARLKHIAHFNGMEVK 288
            ...:..:..:|| :.|..|..|.::.:.| ||:.||.:||:.......||..||.:|..||:.|.
  Fly   257 LAGVIYIVRDWRELSLAVSMPLLMLFSCF-FVLPESPRWLMAVGKTRRAIKILKVMARVNGVRVN 320

  Fly   289 AADFEAFRRNCIVKRKLSNQPEQTA--GIFDLLRTPNLRKVSLLVVFTFMLTSLSFNTISRNVEG 351
            ....|..:|..::.|....:...|.  ||.||.|.||:|:.:|::...:...:..:..:|.....
  Fly   321 RDFVERLQRKLVITRAAETKSSMTTHYGILDLFRGPNMRRKTLIITLIWFANTSVYVGLSYYAPA 385

  Fly   352 MGLSPFVVFSLFAVVVPPSGFI--QGLLQSRVGRKATAFLAMLCTGLLSCALGVALSTEGAQKNV 414
            :|......|.|...|..|:..:  .||  |..||:...|::||..       |||........::
  Fly   386 LGGDEIWNFFLAGAVELPTYLLLWPGL--SYFGRRWILFISMLVG-------GVACVATFLYPDI 441

  Fly   415 TLLLAFALPMRLGISMCYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIHLGTKLAAA 479
            ||||...  .::|||..:.|....||||.||.||..|::...:.:.....|.|.:.|:|.::...
  Fly   442 TLLLYCV--GKMGISSSFVVLPLMASELYPTVVRGLGMSFSSVISMVGPIVIPMINHMGQQMLVL 504

  Fly   480 PSLILALLLLTASGCTLMLPETNNRQLPITLADGEA 515
            |.:::..||:.....:|:||||.||.||.||.:|||
  Fly   505 PLIVMGALLILGGFASLLLPETRNRNLPQTLEEGEA 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	142/538 (26%)
CG14857	NP_650392.1	MFS	126..470	CDD:119392	93/348 (27%)
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	105/408 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458528
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I1789
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	5	4.990